Aronixil

Base Information

Chemical Name:Aronixil
CAS No.:86627-15-8
Molecular Formula:C14H15ClN4O2
Molecular Weight:306.752
Hs Code.:2933599090
Mol file:86627-15-8.mol

Synonyms:1-Dppap;1,2-Benzenediol,4-(2-(propylamino)propyl);1-(3,4-Dihydroxyphenyl)-2-(n-propylamino)propane;N-[4-chloro-6-(2,3-xylidino)-2-pyrimidinyl]-aminoacetic acid;

Suppliers and Price of Aronixil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ARONIXIL 95.00%
5MG
$ 496.24

Total 1 raw suppliers

Chemical Property of Aronixil

Chemical Property:

Vapor Pressure:1.62E-12mmHg at 25°C
Boiling Point:540.5°Cat760mmHg
Flash Point:280.7°C
PSA：87.14000
Density:1.413g/cm³
LogP:3.13290

Purity/Quality:: ARONIXIL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Pharmaceutic aid (vehicle, flavored); pharmaceutic aid (vehicle, sweetened).

Technology Process of Aronixil

There total 4 articles about Aronixil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 86627-16-9
N-[4-chloro-6-(2,3-xylidino)-2-pyrimidinyl]-aminoacetic acid, ethyl ester

: 86627-15-8
N-[4-chloro-6-(2,3-xylidino)-2-pyrimidinyl]-aminoacetic acid

Guidance literature:: With sodium hydroxide; In ethanol; at 60 ℃; for 0.0833333h;
DOI:10.1021/jm00378a016

Reference yield:

: 86626-95-1
6-chloro-N-(2,3-dimethylphenyl)-2-(methylsulfanyl)pyrimidin-4-amine

: 86627-15-8
N-[4-chloro-6-(2,3-xylidino)-2-pyrimidinyl]-aminoacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / 30percent aq. H₂O₂, Na₂WO₄ / acetic acid / 16 h / 20 °C

2: 85 percent / NaH, Et₃N / ethanol / 18 h / Heating

3: 79 percent / 1 N aq. NaOH / ethanol / 0.08 h / 60 °C

With sodium hydroxide; sodium tungstate; dihydrogen peroxide; sodium hydride; triethylamine; In ethanol; acetic acid;
DOI:10.1021/jm00378a016

Reference yield:

: 86627-00-1
6-chloro-N-(2,3-dimethylphenyl)-2-methylsulfonylpyrimidin-4-amine

: 86627-15-8
N-[4-chloro-6-(2,3-xylidino)-2-pyrimidinyl]-aminoacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / NaH, Et₃N / ethanol / 18 h / Heating

2: 79 percent / 1 N aq. NaOH / ethanol / 0.08 h / 60 °C

With sodium hydroxide; sodium hydride; triethylamine; In ethanol;
DOI:10.1021/jm00378a016