3-(Aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one

Base Information

Chemical Name:3-(Aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one
CAS No.:64358-50-5
Molecular Formula:C₁₅H₁₅NO₃
Molecular Weight:257.289
Hs Code.:2932999099
UNII:9RZS3WBN9X
DSSTox Substance ID:DTXSID70982900
Nikkaji Number:J711.897J
Wikidata:Q82969758
ChEMBL ID:CHEMBL2009436

Synonyms:(3H)4'-aminomethyl-4,5',8-trimethylpsoralen;3-(aminomethyl)-2,5,9-trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one;3H-AMT;4'-aminomethyl-4,5',8-trimethylpsoralen;5-AMTP;aminomethylpsoralen;aminomethyltrimethylpsoralen;aminomethyltrioxsalen;aminomethyltrioxsalen hydrochloride

Suppliers and Price of 3-(Aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4''-Aminomethyl-4,5'',8-trimethylpsoralen
0.5mg
$ 325.00

Cayman Chemical
4'-Aminomethyl-4,5',8-trimethylpsoralen ≥98%
10mg
$ 190.00

Cayman Chemical
4'-Aminomethyl-4,5',8-trimethylpsoralen ≥98%
5mg
$ 102.00

Cayman Chemical
4'-Aminomethyl-4,5',8-trimethylpsoralen ≥98%
1mg
$ 28.00

American Custom Chemicals Corporation
4'-AMINOMETHYL-4,5',8-TRIMETHYLPSORALEN 95.00%
5MG
$ 499.50

AK Scientific
3-(Aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one
10mg
$ 336.00

Total 4 raw suppliers

Chemical Property of 3-(Aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one

Chemical Property:

Boiling Point:453.4oC at 760 mmHg
Flash Point:228oC
PSA：69.37000
LogP:3.62340
Storage Temp.:2-8°C
Solubility.:H2O: 1 mg/mL
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:257.10519334
Heavy Atom Count:19
Complexity:420

Purity/Quality:

99% ^*data from raw suppliers

4''-Aminomethyl-4,5'',8-trimethylpsoralen ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C
Statements: 20/21/22-34-40
Safety Statements: 26-27-36-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=CC(=O)OC2=C(C3=C(C=C12)C(=C(O3)C)CN)C
Uses 4''-Aminomethyl-4,5'',8-trimethylpsoralen is a bioactive molecule able to intercalates into double-stranded DNA.

Technology Process of 3-(Aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one

There total 4 articles about 3-(Aminomethyl)-2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 62442-58-4
4'-N-Phthalimidomethyl-4,5',8-trimethylpsoralen

: 64358-50-5
4’-aminomethyl-4,5’,8-trimethylpsoralen

Guidance literature:: With hydrazine hydrate; In ethanol; for 6h; Heating;
DOI:10.1002/jhet.5570220119

Reference yield: 76.0%

: 62442-57-3
4'-chloromethyl-4,5',8-trimethylpsoralen

: 64358-50-5
4’-aminomethyl-4,5’,8-trimethylpsoralen

Guidance literature:: 4'-chloromethyl-4,5',8-trimethylpsoralen; With potassium phtalimide; In N,N-dimethyl-formamide; at 100 ℃; for 6h;

With hydrazine hydrate; In ethanol; for 6h; Reflux;
DOI:10.1002/chem.202101171

Reference yield:

: 3902-71-4
trioxsalen

: 64358-50-5
4’-aminomethyl-4,5’,8-trimethylpsoralen

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / trifluoromethanesulfonic acid, trifluoroacetic acid / CH₂Cl₂ / 6 h / Ambient temperature

2: 80 percent / 85percent aq. hydrazine / ethanol / 6 h / Heating

With trifluorormethanesulfonic acid; hydrazine hydrate; trifluoroacetic acid; In ethanol; dichloromethane;
DOI:10.1002/jhet.5570220119