62442-58-4

Basic information

• Product Name: 2-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methyl]-1H-isoindole-1,3(2H)-dione
• CAS NO: 62442-58-4
• Molecular Formula: C₂₃H₁₇NO₅
• Molecular Weight: 387.3848
• Mol File: 62442-58-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 601.7°C at 760 mmHg
• Flash Point: 317.7°C
• Density: 1.403g/cm³
• Vapor Pressure: 1.96E-14mmHg at 25°C
• Refractive Index: 1.684
• CAS DataBase Reference: 2-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methyl]-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methyl]-1H-isoindole-1,3(2H)-dione(62442-58-4)
• EPA Substance Registry System: 2-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methyl]-1H-isoindole-1,3(2H)-dione(62442-58-4)

Safety Data

• Hazardous Substances Data: 62442-58-4(Hazardous Substances Data)

Usage

Molecular structure

A complex chemical compound with a unique structure, composed of a furochromene ring system (a fusion of furan and chromene rings) and an isoindole-dione ring.

Functional groups

Contains a methyl group (-CH3) and a carbonyl group (C=O).

Potential applications

Due to its complex structure and multiple functional groups, this chemical may have pharmaceutical, medicinal, or biological applications.

Drug candidate potential

It may have potential as a drug candidate, particularly for conditions that can be targeted by isoindole-dione derivatives.

Further research

Additional research and testing would be needed to determine the specific properties and potential uses of this compound.

Upstream product

• 118-29-6 2-(hydroxymethyl)-1H-isoindole-1,3(2H)-dione 
• 3902-71-4 trioxsalen 
• 144-55-8 sodium hydrogencarbonate 
• 62442-57-3 4'-chloromethyl-4,5',8-trimethylpsoralen 
• 1074-82-4 potassium phtalimide 
• 68-12-2 N,N-dimethyl-formamide 
• 41997-10-8 bis (phthalimidomethyl) ether 

Downstream Products

• 64358-50-5 4’-aminomethyl-4,5’,8-trimethylpsoralen 

Relevant articles and documents

Aminomethyl psoralens. Electrophilic substitutions of hydroxymethylphthamide on linear furocoumarins

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Process for the preparation of di- and trialkyl-4'-phthalimidomethylfurocoumarins

Di- and trialkyl-4'-phthalimidomethyl-furocoumarins are prepared by reacting di- or trialkyl-furocoumarins in the presence of an acid and, if appropriate, of a polar solvent with a compound of the formula (I) STR1 in which R" represents hydrogen, a second phthalimidomethyl group, C1 - to C4 -alkyl or C1 - to C6 -acyl, where, when using trialkyl-furocoumarins, R" does not represent hydrogen.

Psoralens

New psoralen compounds have been synthesized. The compounds all include the addition of substituent groups at the 4'-position on the basic trioxsalen structure. Specifically, the compounds have the structure STR1 wherein STR2 where R is a mono or dicyclic radical which can contain one additional hetero atom in the nitrogen containing ring. The new substituted psoralens exhibit high solubility in aqueous solution and low dissociation constants from deoxyribonucleic acid (DNA), as well as a reactivity with ribonucleic acids (RNA).