5-Methyl-5-phenylfuran-2(5H)-one

Base Information

• Chemical Name: 5-Methyl-5-phenylfuran-2(5H)-one
• CAS No.: 53774-21-3
• Molecular Formula: C11H10O2
• Molecular Weight: 174.199
• Hs Code.: 2932209090
• Mol file: 53774-21-3.mol

Synonyms:2(5H)-Furanone,5-methyl-5-phenyl;5-methyl-5-phenyl-5H-furan-2-one;4-Methyl-4-phenylbut-2-enolid;5-Methyl-5-phenyl-2(5H)-furanone;5-methyl-5-phenyl-2,5-dihydrofuran-2-one;4-Methyl-4-phenylbut-2-enolide;5-methyl-5-phenyl butenolide;

Chemical Property of 5-Methyl-5-phenylfuran-2(5H)-one

Chemical Property:

• PSA: 26.30000
• LogP: 2.01480

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Methyl-5-phenylfuran-2(5H)-one

There total 47 articles about 5-Methyl-5-phenylfuran-2(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Benzenesulfonyl-5-methyl-5-phenyl-dihydro-furan-2-one (112751-94-7,112751-95-8) → 5-methyl-5-phenyl-2,5-dihydrofuran-2-one (53774-21-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 ℃; for 0.416667h;

DOI:10.1016/S0040-4039(00)96063-5

Reference yield: 99.0%

5-Methyl-5-phenyl-4-(toluene-4-sulfonyl)-dihydro-furan-2-one → 5-methyl-5-phenyl-2,5-dihydrofuran-2-one (53774-21-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; Ambient temperature;

DOI:10.1016/0040-4020(95)00026-5

Reference yield: 95.0%

4-Bromo-5-methyl-5-phenyl-5H-furan-2-one (98761-44-5) → 5-methyl-5-phenyl-2,5-dihydrofuran-2-one (53774-21-3)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In tetrahydrofuran; Heating;

DOI:10.1021/jo00224a044

upstream raw materials:

2-Phenyl-3-butyn-2-ol

carbon monoxide

(1-Methyl-1-phenyl-prop-2-ynyloxy)-triphenyl-silane

4-Benzenesulfonyl-5-methyl-5-phenyl-dihydro-furan-2-one

Downstream raw materials:

(Z)-5-Methyl-2-phenylhexen-3-diol-2,5

methyl 2-hydroxy-2-phenylpropanoate