4-(2-Aminoethyl)-5-fluoro-1,2-benzenediol

Base Information

Chemical Name:4-(2-Aminoethyl)-5-fluoro-1,2-benzenediol
CAS No.:71144-39-3
Molecular Formula:C8H10 F N O2
Molecular Weight:171.171
Hs Code.:
DSSTox Substance ID:DTXSID10991450
Nikkaji Number:J356.109G
Wikidata:Q82981218
ChEMBL ID:CHEMBL41818
Mol file:71144-39-3.mol

Synonyms:5-fluorodopamine

Suppliers and Price of 4-(2-Aminoethyl)-5-fluoro-1,2-benzenediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4-(2-Aminoethyl)-5-fluoro-1,2-benzenediol

Chemical Property:

Vapor Pressure:1.56E-05mmHg at 25°C
Boiling Point:355.1°C at 760 mmHg
Flash Point:168.6°C
PSA：66.48000
LogP:1.43840
XLogP3:0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:171.06955672
Heavy Atom Count:12
Complexity:145

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CC(=C1O)O)F)CCN

Technology Process of 4-(2-Aminoethyl)-5-fluoro-1,2-benzenediol

There total 1 articles about 4-(2-Aminoethyl)-5-fluoro-1,2-benzenediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75290-51-6
3,4-dihydroxy-6-fluoro-L-phenylalanine

: 71144-39-3
6-Fluorodopamine

Guidance literature:: With L-amino acid decarboxylase; for 2h; incubation;

Reference yield: 44.0%

: 4-carboxy-2-cyano-N,N,N-trimethylbenzenaminium trifluoromethanesulfonate

: 71144-39-3
6-Fluorodopamine

: N-(4-trimethylammonium-3-cyanobenzoyl)-6-fluorodopamin triflate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; diisopropyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide; for 8h;

Reference yield:

: 71144-39-3
6-Fluorodopamine

: C₈H₈⁽³⁾H₂FNO₂

Guidance literature:: Multi-step reaction with 2 steps

1: bromine; acetic acid

2: tritium; HCl / palladium on carbon / 20 °C

With hydrogenchloride; tritium; bromine; acetic acid; palladium on activated charcoal;
DOI:10.1080/00397910500466504