75290-51-6

Basic information

• Product Name: CAINDEXNAME:L-TYROSINE,2-FLUORO-5-HYDROXY-
• Synonyms: CAINDEXNAME:L-TYROSINE,2-FLUORO-5-HYDROXY- ;fluorodopa F 18;2-Fluoro-5-hydroxy-L-tyrosine;2-Fluoro-5-hydroxytyrosine;3,4-Dihydroxy-6-fluorophenylalanine;6-Fluoro-dopa;6-Fluoro-L-dopa;L-Tyrosine, 2-fluoro-5-hydroxy-
• CAS NO: 75290-51-6
• Molecular Formula: C₉H₁₀FNO₄
• Molecular Weight: 215.1784032
• Product Categories: Amino Acids & Derivatives;Aromatics;Chiral Reagents
• Mol File: 75290-51-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 200-203°C
• Boiling Point: 465.3°C at 760 mmHg
• Flash Point: 235.2°C
• Appearance: /
• Density: 1.553g/cm³
• Vapor Pressure: 1.85E-09mmHg at 25°C
• Refractive Index: 1.629
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: Water
• PKA: 2.24±0.25(Predicted)
• CAS DataBase Reference: CAINDEXNAME:L-TYROSINE,2-FLUORO-5-HYDROXY-(CAS DataBase Reference)
• NIST Chemistry Reference: CAINDEXNAME:L-TYROSINE,2-FLUORO-5-HYDROXY-(75290-51-6)
• EPA Substance Registry System: CAINDEXNAME:L-TYROSINE,2-FLUORO-5-HYDROXY-(75290-51-6)

Safety Data

• Hazardous Substances Data: 75290-51-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10FNO4/c10-5-3-8(13)7(12)2-4(5)1-6(11)9(14)15/h2-3,6,12-13H,1,11H2,(H,14,15)/t6-/m0/s1

Upstream product

• 853759-49-6 N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-fluoro-L-phenylalanine methyl ester 
• 117831-95-5 (S)-3-(3,4-Dimethoxy-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid ethyl ester 
• 59-92-7 levodopa 
• 300-48-1 3-O-methyldopa 
• 476359-34-9 (2R)-N-[(2S)-2-((diphenylmethylidene)amino)-2-(2'-fluoro-4',5'-dimethoxybenzyl)-ethan-1-oyl]bornane-10,2-sultam 
• 476359-38-3 (2R)-N-[(2S)-2-amino-2-(2'-fluoro-4',5'-dimethoxybenzyl)-ethan-1-oyl]bornane-10,2-sultam 
• 91407-48-6 2-(chloromethyl)-4,5-dimethoxy-1-fluorobenzene 
• 476359-42-9 6-fluoro-L-3,4-dimethoxyphenylalanine 
• 75290-49-2 L-3-methoxy-4-hydroxyphenylalanine ethyl ester 
• 117831-96-6 (S)-3-(2-Fluoro-4,5-dimethoxy-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid ethyl ester 

Downstream Products

• 71144-39-3 6-Fluorodopamine 

Relevant articles and documents

Opportunities for isotopic labelling via phase-tagged synthesis with organogermanium linkers

Strategies for the use of germanium-based linkers for the phase-tagged synthesis of isotopically labelled intermediates are described. Protocols of potential use in the devolatilization of volatile intermediates prepared from [14C]-CO2/su

Convenient syntheses of 2-, 5- and 6-fluoro- and 2,6-difluoro-L-DOPA

Alkylation under phase transfer conditions of the chiral glycine synthon 2 (prepared from the commercially available Oppolzer chiral sultam) with fluorinated analogues of 3,4-dimethoxybenzyl chloride proceeded with high diastereoselectivity. Hydrolysis of

FLUORINATION OF SUBSTITUTED VERATROLES VIA REGIOSELECTIVE MERCURATION

A regioselective aromatic ring fluorination of substituted veratroles was achieved via a mercuration-fluorodemercuration reaction.