Costol

Base Information

Chemical Name:Costol
CAS No.:515-20-8
Molecular Formula:C15H24O
Molecular Weight:220.35
Hs Code.:
Mol file:515-20-8.mol

Synonyms:

Suppliers and Price of Costol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Costol

Chemical Property:

Melting Point:215 °C
Boiling Point:170-180 °C(Press: 11 Torr)
PKA:14.77±0.10(Predicted)
Density:0.9797 g/cm3(Temp: 21 °C)

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses β-Costol is a component in essential oil from plant extract and exhibits antibacterial and antifungal activities

Technology Process of Costol

There total 17 articles about Costol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: dimethyl (trans-4aβ-methyl-1-methylene-7β-decalinyl)malonate

: 4700-80-5
trans-7β-(2-hydroxy-1-methylethyl)-4aβ-methyl-1-methylenedecalin

: 515-20-8,69427-73-2,72057-07-9,77171-51-8,97371-99-8
dl-β-costol

Guidance literature:: With sodium hydride; sodium bis(2-methoxyethoxy)aluminium dihydride; Yield given. Multistep reaction; 1.) DME, 24 h, reflux, 2.) benzene DME, 1 h, reflux;
DOI:10.1246/bcsj.53.2642

Reference yield:

: 347377-91-7
germacra-1⁽¹⁰⁾,4,11⁽¹³⁾-trien-12-ol

: 69427-73-2,72057-07-9,77171-51-8,97371-99-8,515-20-8
(+)-β-costol

: 65018-14-6
γ-costol

: 65018-15-7
2-(2R,4aR,8aR)-(4a,8-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl)prop-2-en-1-ol

Guidance literature:: With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 0.116667h;
DOI:10.1016/S0031-9422(01)00291-6

Reference yield:

: 2α-hydroxy-4aβ-methyldecalin-8-one

: 515-20-8,69427-73-2,72057-07-9,77171-51-8,97371-99-8
dl-β-costol

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / pyridine / 20 h / 5 °C

2: 82 percent / 1,2-dimethoxy-ethane / 36 h / Heating

3: 86 percent / benzene / 20 h / Ambient temperature

4: 1.) NaH, 2.) NaAl(OCH₂CH₂OCH₃)2H₂ / 1.) DME, 24 h, reflux, 2.) benzene DME, 1 h, reflux

With pyridine; sodium hydride; sodium bis(2-methoxyethoxy)aluminium dihydride; In 1,2-dimethoxyethane; benzene;
DOI:10.1246/bcsj.53.2642