6,7,8-Trimethoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one

Base Information

Chemical Name:6,7,8-Trimethoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one
CAS No.:53948-03-1
Molecular Formula:C19H18O6
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID10696953
Wikidata:Q82626744
Mol file:53948-03-1.mol

Synonyms:53948-03-1;6,7,8-trimethoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one;DTXSID10696953;A829855;6,7,8-trimethoxy-3-(4-methoxyphenyl)chromen-4-one;6,7,8-Trimethoxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Suppliers and Price of 6,7,8-Trimethoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 6,7,8-Trimethoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:342.11033829
Heavy Atom Count:25
Complexity:496

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=COC3=C(C(=C(C=C3C2=O)OC)OC)OC

Technology Process of 6,7,8-Trimethoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one

There total 4 articles about 6,7,8-Trimethoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13909-73-4
2',3',4'-trimethoxyacetophenone

: 53948-03-1
C₁₉H₁₈O₆

Guidance literature:: Multi-step reaction with 5 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / Reflux; Inert atmosphere

2: boron trifluoride diethyl etherate / 48 h / Reflux

3: 3 h / 80 °C

4: iodine / methanol / 20 °C

5: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran; water / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; boron trifluoride diethyl etherate; iodine; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; dichloromethane; water; 5: |Suzuki Coupling;
DOI:10.1002/cmdc.201200561

Reference yield:

: 1453477-76-3
3-(dimethylamino)-1-(2-hydroxy-3,4,5-trimethoxyphenyl)prop-2-en-1-one

: 53948-03-1
C₁₉H₁₈O₆

Guidance literature:: Multi-step reaction with 2 steps

1: iodine / methanol / 20 °C

2: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran; water / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; iodine; potassium carbonate; In tetrahydrofuran; methanol; water; 2: |Suzuki Coupling;
DOI:10.1002/cmdc.201200561

Reference yield:

: 30225-96-8
1-(2-hydroxy-3,4,5-trimethoxyphenyl)ethan-1-one

: 53948-03-1
C₁₉H₁₈O₆

Guidance literature:: Multi-step reaction with 3 steps

1: 3 h / 80 °C

2: iodine / methanol / 20 °C

3: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran; water / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; iodine; potassium carbonate; In tetrahydrofuran; methanol; water; 3: |Suzuki Coupling;
DOI:10.1002/cmdc.201200561