1H-2-Benzazepine, 2,3,4,5-tetrahydro-2-(phenylmethyl)-

Base Information

Chemical Name:1H-2-Benzazepine, 2,3,4,5-tetrahydro-2-(phenylmethyl)-
CAS No.:54311-89-6
Molecular Formula:C17H19N
Molecular Weight:237.345
Hs Code.:
DSSTox Substance ID:DTXSID10480112
Wikidata:Q82314656

Synonyms:54311-89-6;1H-2-Benzazepine, 2,3,4,5-tetrahydro-2-(phenylmethyl)-;DTXSID10480112

Suppliers and Price of 1H-2-Benzazepine, 2,3,4,5-tetrahydro-2-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1H-2-Benzazepine, 2,3,4,5-tetrahydro-2-(phenylmethyl)-

Chemical Property:

Melting Point:44-46 °C
Boiling Point:348.7±11.0 °C(Predicted)
PSA：3.24000
Density:1.062±0.06 g/cm3(Predicted)
LogP:3.57290
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:237.151749610
Heavy Atom Count:18
Complexity:244

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=CC=CC=C2CN(C1)CC3=CC=CC=C3

Technology Process of 1H-2-Benzazepine, 2,3,4,5-tetrahydro-2-(phenylmethyl)-

There total 9 articles about 1H-2-Benzazepine, 2,3,4,5-tetrahydro-2-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 7216-22-0
2,3,4,5-tetrahydro-1H-benzo[c]azepine

: 100-39-0
benzyl bromide

: 54311-89-6
2-benzyl-2,3,4,5-tetrahydro-1H-benzo[c]azepine

Guidance literature:: 2,3,4,5-tetrahydro-1H-benzo[c]azepine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃;

benzyl bromide; In tetrahydrofuran; hexane; at -78 - -40 ℃; for 1h;
DOI:10.1016/j.tetlet.2005.07.110

Reference yield: 73.0%

: 136863-23-5
3-[2-(hydroxymethyl)phenyl]propan-1-ol

: 100-46-9
benzylamine

: 54311-89-6
2-benzyl-2,3,4,5-tetrahydro-1H-benzo[c]azepine

Guidance literature:: 3-[2-(hydroxymethyl)phenyl]propan-1-ol; With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 3h; Inert atmosphere;

benzylamine; In methanol; at 20 ℃; for 7h;
DOI:10.1080/00397911.2014.928327

Reference yield:

: 14807-28-4
2-(3-oxopropyl)benzaldehyde

: 100-46-9
benzylamine

: 54311-89-6
2-benzyl-2,3,4,5-tetrahydro-1H-benzo[c]azepine

Guidance literature:: 2-(3-oxopropyl)benzaldehyde; benzylamine; In tetrahydrofuran; dichloromethane; at 20 ℃; for 0.166667h;

With sodium cyanoborohydride; acetic acid; In tetrahydrofuran; dichloromethane; at 20 ℃; for 3h;
DOI:10.1016/j.jfluchem.2020.109466