MMP-13 Inhibitor

Base Information

Chemical Name:MMP-13 Inhibitor
CAS No.:544678-85-5
Molecular Formula:C22H20F2N4O2
Molecular Weight:410.423
Hs Code.:29335990
Mol file:544678-85-5.mol

Synonyms:MMP-13 INHIBITOR;N4,N6-Bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide;

Suppliers and Price of MMP-13 Inhibitor

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
DB04760 >98%
1 g
$ 2000.00

Crysdot
N4,N6-Bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide 97%
1g
$ 198.00

Crysdot
N4,N6-Bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide 97%
5g
$ 594.00

ChemScene
DB04760 98.45%
50mg
$ 1350.00

ChemScene
DB04760 98.45%
1mg
$ 100.00

ChemScene
DB04760 98.45%
10mg
$ 480.00

ChemScene
DB04760 98.45%
5mg
$ 280.00

Chemenu
N4,N6-bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide 97%
1g
$ 204.00

Chemenu
N4,N6-bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide 97%
5g
$ 561.00

Cayman Chemical
MMP-13 Inhibitor ≥98%
10mg
$ 535.00

Total 13 raw suppliers

Chemical Property of MMP-13 Inhibitor

Chemical Property:

Boiling Point:684.6±55.0 °C(Predicted)
PKA:11.79±0.46(Predicted)
PSA：83.98000
Density:1.286±0.06 g/cm3(Predicted)
LogP:4.01340
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:≤0.5mg/ml in ethanol;2mg/ml in DMSO;2mg/ml in dimethyl formamide

Purity/Quality:

97% ^*data from raw suppliers

DB04760 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description MMP-13 Inhibitor is a pyrimidine dicarboxamide that inhibits matrix metalloproteinase-13 (MMP-13, also known as collagenase-3) with an IC50 value of 8 nM. MMP-13 Inhibitor binds to pockets that are unique to MMP-13, rather than the catalytic zinc, and thus is specific for MMP-13 over other MMPs. MMP-13 Inhibitor blocks osterix-dependent calcification of matrices in limb bud cells during endochondral ossification.

Technology Process of MMP-13 Inhibitor

There total 2 articles about MMP-13 Inhibitor which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%