Propanedioic acid, [[[(4-methylphenyl)sulfonyl]oxy]imino]-, dimethyl ester

Base Information

Chemical Name:Propanedioic acid, [[[(4-methylphenyl)sulfonyl]oxy]imino]-, dimethyl ester
CAS No.:54972-12-2
Molecular Formula:C12H13NO7S
Molecular Weight:315.304
Hs Code.:

Synonyms:(toluene-4-sulfonyloxyimino)-malonic acid dimethyl ester;

Suppliers and Price of Propanedioic acid, [[[(4-methylphenyl)sulfonyl]oxy]imino]-, dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Dimethyl 2-((tosyloxy)imino)malonate ≥95%
1 g
$ 109.00

Total 1 raw suppliers

Chemical Property of Propanedioic acid, [[[(4-methylphenyl)sulfonyl]oxy]imino]-, dimethyl ester

Chemical Property:

Melting Point:91 - 96 °C
Boiling Point:418.4±38.0 °C(Predicted)
PSA：116.71000
Density:1.34±0.1 g/cm3(Predicted)
LogP:1.48310

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dimethyl 2-((tosyloxy)imino)malonate ≥95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses As demonstrated by Laszlo Kürti′s lab, ketomalonate oxime O-sulfonates act as doubly N-electrophilic linchpin reagents towards strong C-nucleophiles such as alkyl- and arylmetals (e.g., Grignard reagents). Thus, symmetrical dialkyl- as well as diarylamines may be directly prepared at low tempretatures and in the absence of transition metal catalysts. Other ketomalonate oxime O-sulfonates include 902918, 902705 and 902624.

Technology Process of Propanedioic acid, [[[(4-methylphenyl)sulfonyl]oxy]imino]-, dimethyl ester

There total 4 articles about Propanedioic acid, [[[(4-methylphenyl)sulfonyl]oxy]imino]-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 42937-74-6
dimethyl 2-(hydroxyimino)malonate

: 98-59-9
p-toluenesulfonyl chloride

: 54972-12-2
dimethyl 2-((tosyloxy)imino)malonate

Guidance literature:: With triethylamine; In diethyl ether; at 0 - 20 ℃; for 6.5h;
DOI:10.1021/ol2021252

Reference yield: 83.0%

: 54972-12-2
dimethyl 2-((tosyloxy)imino)malonate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 6h; Inert atmosphere;

Reference yield:

: 108-59-8
malonic acid dimethyl ester

: 54972-12-2
dimethyl 2-((tosyloxy)imino)malonate

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / NaNO₂, H₂SO₄ / H₂O / 40 deg C, 1 h then r.t., overnight

2: 84 percent / pyridine / 10 °C

With pyridine; sulfuric acid; sodium nitrite; In water;