1-Imidazolidinecarboxylic acid, 2-oxo-, phenylmethyl ester

Base Information

• Chemical Name: 1-Imidazolidinecarboxylic acid, 2-oxo-, phenylmethyl ester
• CAS No.: 55150-34-0
• Molecular Formula: C₁₁H₁₂N₂O₃
• Molecular Weight: 220.228
• Mol file: 55150-34-0.mol

Synonyms:

Chemical Property of 1-Imidazolidinecarboxylic acid, 2-oxo-, phenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Imidazolidinecarboxylic acid, 2-oxo-, phenylmethyl ester

There total 6 articles about 1-Imidazolidinecarboxylic acid, 2-oxo-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

2-oxoimidazolidine-1-carbonyl chloride (13214-53-4) + benzyl alcohol (100-51-6,185532-71-2) → 1-Benzyloxycarbonylimidazolidin-2-one (55150-34-0)

Guidance literature:

In benzene; Heating;

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → 1-Benzyloxycarbonylimidazolidin-2-one (55150-34-0)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / 16 h / Heating

2: pyrrolidine / dioxane / 7 h / Heating

With pyrrolidine; In 1,4-dioxane; benzene;

DOI:10.1039/P19950002953

Reference yield:

3-(benzyloxycarbonylamino)propanoic acid (2304-94-1) → 1-Benzyloxycarbonylimidazolidin-2-one (55150-34-0)

Guidance literature:

With diphenylphosphoranyl azide; triethylamine; benzyl alcohol; Yield given. Multistep reaction; 1.) benzene, reflux, 30 min, 2.) reflux, overnight;

DOI:10.1021/jo00145a001

upstream raw materials:

3-(benzyloxycarbonylamino)propanoic acid

2-oxoimidazolidine-1-carbonyl chloride

benzyl alcohol

pyrrolidine

Downstream raw materials:

1,3-Bis(benzyloxycarbonyl)imidazolidin-2-one