2-Oxoimidazolidine-1,3-dicarboxylic acid dibenzyl ester

Base Information

• Chemical Name: 2-Oxoimidazolidine-1,3-dicarboxylic acid dibenzyl ester
• CAS No.: 173300-87-3
• Molecular Formula: C₁₉H₁₈N₂O₅
• Molecular Weight: 354.362
• DSSTox Substance ID: DTXSID901193013
• Nikkaji Number: J695.526F
• Mol file: 173300-87-3.mol

Synonyms:DTXSID901193013;2-Oxoimidazolidine-1,3-dicarboxylic acid dibenzyl ester;1,3-Bis(phenylmethyl) 2-oxo-1,3-imidazolidinedicarboxylate;173300-87-3

Chemical Property of 2-Oxoimidazolidine-1,3-dicarboxylic acid dibenzyl ester

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 354.12157168
• Heavy Atom Count: 26
• Complexity: 468

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CN(C(=O)N1C(=O)OCC2=CC=CC=C2)C(=O)OCC3=CC=CC=C3

Technology Process of 2-Oxoimidazolidine-1,3-dicarboxylic acid dibenzyl ester

There total 2 articles about 2-Oxoimidazolidine-1,3-dicarboxylic acid dibenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Benzyloxycarbonylimidazolidin-2-one (55150-34-0) → 1,3-Bis(benzyloxycarbonyl)imidazolidin-2-one (173300-87-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N

2: benzene / 16 h / Heating

With triethylamine; In benzene;

DOI:10.1039/P19950002953

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) + 1-Benzyloxycarbonyl-3-trimethylsilylimidazolidin-2-one → 1,3-Bis(benzyloxycarbonyl)imidazolidin-2-one (173300-87-3)

Guidance literature:

In benzene; for 16h; Yield given; Heating;

DOI:10.1039/P19950002953

Reference yield:

1,3-Bis(benzyloxycarbonyl)imidazolidin-2-one (173300-87-3) → 1-benzyloxycarbonylpyrrolidine (25070-74-0) + 1-Benzyloxycarbonylimidazolidin-2-one (55150-34-0)

Guidance literature:

With pyrrolidine; In 1,4-dioxane; for 7h; Yield given. Yields of byproduct given; Heating;

DOI:10.1039/P19950002953

upstream raw materials:

benzyl chloroformate

1-Benzyloxycarbonylimidazolidin-2-one

Downstream raw materials:

1-benzyloxycarbonylpyrrolidine

1-Benzyloxycarbonylimidazolidin-2-one