Carbamic chloride, methyl(2-phenylethyl)-

Base Information

• Chemical Name: Carbamic chloride, methyl(2-phenylethyl)-
• CAS No.: 55246-60-1
• Molecular Formula: C₁₀H₁₂ClNO
• Molecular Weight: 197.664
• Mol file: 55246-60-1.mol

Synonyms:Methyl-phenaethyl-carbamoylchlorid;

Chemical Property of Carbamic chloride, methyl(2-phenylethyl)-

Chemical Property:

• PSA: 20.31000
• LogP: 2.51970

Purity/Quality:

99%min ^*data from raw suppliers

CID13362293 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamic chloride, methyl(2-phenylethyl)-

There total 2 articles about Carbamic chloride, methyl(2-phenylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosgene (75-44-5) + N-Methyl-N-phenethylamine (589-08-2) → methyl-phenethyl-carbamoyl chloride (55246-60-1)

Guidance literature:

In 1,4-dioxane; at 0 - 20 ℃;

DOI:10.1016/j.bmcl.2005.10.108

Reference yield:

N-methyl-N-phenethylformamide (90784-34-2) → methyl-phenethyl-carbamoyl chloride (55246-60-1)

Guidance literature:

With thionyl chloride;

Reference yield:

methyl-phenethyl-carbamoyl chloride (55246-60-1) → C21H34N4O3

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄ / dioxane

2: PPTS / tetrahydrofuran

With pyridinium p-toluenesulfonate; hydrazine; In tetrahydrofuran; 1,4-dioxane;

DOI:10.1016/j.bmcl.2005.10.108

upstream raw materials:

N-methyl-N-phenethylformamide

phosgene

N-Methyl-N-phenethylamine

Downstream raw materials:

N--carbaminsaeureaethylester

N-methyl-N-phenethyl-urea

C₁₁H₁₇N₃O

Refernces