Acetamide, N-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-(phenylmethyl)ethyl]-, (S)-

Base Information

Chemical Name:Acetamide, N-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-(phenylmethyl)ethyl]-, (S)-
CAS No.:55604-95-0
Molecular Formula:C15H16N2O5
Molecular Weight:304.302
Hs Code.:

Synonyms:(S)-2-Acetylamino-3-phenyl-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester;N-acetyl-L-phenylalanine N-hydroxysuccinimide ester;

Suppliers and Price of Acetamide, N-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-(phenylmethyl)ethyl]-, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetamide, N-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-(phenylmethyl)ethyl]-, (S)-

Chemical Property:

PSA：92.78000
LogP:0.66980

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Acetamide, N-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-(phenylmethyl)ethyl]-, (S)-

There total 2 articles about Acetamide, N-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-(phenylmethyl)ethyl]-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 2018-61-3
(S)-2-acetylamino-3-phenylpropanoic acid

: 55604-95-0
N-acetyl-L-phenylalanine N-hydroxysuccinimide ester

Guidance literature:: With dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 3.5h;
DOI:10.1021/ja207133t

Reference yield:

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 5469-44-3
2-methyl-4-benzyl-4H-oxazolin-5-one

: 55604-95-0
N-acetyl-L-phenylalanine N-hydroxysuccinimide ester

: 56186-57-3
Ac-D-Phe-OSu

Guidance literature:: In 1,4-dioxane; at 20 ℃; for 24h; Product distribution; other solvent;
DOI:10.1007/BF00947825

Reference yield: 77.0%

: 55604-95-0
N-acetyl-L-phenylalanine N-hydroxysuccinimide ester

: 105-56-6
ethyl 2-cyanoacetate

: 372965-52-1
ethyl 4-acetylamino-2-cyano-3-hydroxy-5-phenylpent-2-enoate

Guidance literature:: ethyl 2-cyanoacetate; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 1h;

N-acetyl-L-phenylalanine N-hydroxysuccinimide ester; In tetrahydrofuran; at 0 ℃; for 3h;
DOI:10.1002/jhet.5570380416