5-[bis(4-chlorophenyl)methyl]pyrimidine

Base Information

Chemical Name:5-[bis(4-chlorophenyl)methyl]pyrimidine
CAS No.:26766-37-0
Molecular Formula:C17H12 Cl2 N2
Molecular Weight:315.1966
Hs Code.:

Synonyms:Pyrimidine,5-[bis(p-chlorophenyl)methyl]- (8CI); 5-Bis[(4-chlorophenyl)methyl]pyrimidine;LY 56110; NSC 626917

Suppliers and Price of 5-[bis(4-chlorophenyl)methyl]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-[bis(4-chlorophenyl)methyl]pyrimidine

Chemical Property:

Vapor Pressure:1.79E-07mmHg at 25°C
Boiling Point:438.3°Cat760mmHg
Flash Point:251.5°C
Density:1.296g/cm³

Purity/Quality:: >98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-[bis(4-chlorophenyl)methyl]pyrimidine

There total 4 articles about 5-[bis(4-chlorophenyl)methyl]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 26766-35-8
α,α-bis(4-chlorophenyl)-5-pyrimidinemethanol

: 26766-37-0
α,α-bis(4-chlorophenyl)-5-methylpyrimidine

Guidance literature:: With hydrogenchloride; acetic acid; tin(ll) chloride; at 20 ℃; Reflux;
DOI:10.1021/jm2015809

Reference yield: 22.0%

: 26766-35-8
α,α-bis(4-chlorophenyl)-5-pyrimidinemethanol

: 26766-37-0
α,α-bis(4-chlorophenyl)-5-methylpyrimidine

: 108395-11-5
5--1,4,5,6-tetrahydropyrimidine

: 108395-10-4
5--1,6-dihydropyrimidine

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jm00391a016

Reference yield:

: 90-98-2
4,4'-Dichlorobenzophenone

: 26766-37-0
α,α-bis(4-chlorophenyl)-5-methylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 55 percent / n-BuLi / tetrahydrofuran; hexane / -95 - 20 °C

2: 1.) anh. SnCl₂, conc. HCl, 2.) pyridine / 1.) glacial acetic acid, reflux, 2.) THF, 30 min

With pyridine; hydrogenchloride; n-butyllithium; tin(ll) chloride; In tetrahydrofuran; hexane;
DOI:10.1021/jm00391a016