1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 4-[(4-fluorophenyl)methyl]-8-(1-methylethyl)-3-[[4-(2-methylpropoxy)phen yl]methyl]-, monohydrochloride

Base Information

• Chemical Name: 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 4-[(4-fluorophenyl)methyl]-8-(1-methylethyl)-3-[[4-(2-methylpropoxy)phen yl]methyl]-, monohydrochloride
• CAS No.: 561313-98-2
• Molecular Formula: C₂₈H₃₇FN₂O₃*ClH
• Molecular Weight: 505.073

Synonyms:

Chemical Property of 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 4-[(4-fluorophenyl)methyl]-8-(1-methylethyl)-3-[[4-(2-methylpropoxy)phen yl]methyl]-, monohydrochloride

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Useful:

Technology Process of 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 4-[(4-fluorophenyl)methyl]-8-(1-methylethyl)-3-[[4-(2-methylpropoxy)phen yl]methyl]-, monohydrochloride

There total 1 articles about 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 4-[(4-fluorophenyl)methyl]-8-(1-methylethyl)-3-[[4-(2-methylpropoxy)phen yl]methyl]-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

→ 4-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-8-isopropyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one, hydrochloride (561313-98-2)

Guidance literature:

Reference yield: 29.0%

4-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-2-oxo-1-oxa-3,8-diaza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester (561313-88-0) + 4-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-8-isopropyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one, hydrochloride (561313-98-2) → 4-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-8-[2-(2-oxo-imidazolidin-1-yl)-ethyl]-1-oxa-3,8-diaza-spiro[4.5]decan-2-one, hydrochloride

Guidance literature:

Reference yield: 10.0%

4-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-2-oxo-1-oxa-3,8-diaza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester (561313-88-0) + 4-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-8-isopropyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one, hydrochloride (561313-98-2) → 8-Cyclopropylmethyl-4-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-oxa-3.8-diaza-spiro[4.5]decan-2-one, hydrochloride

Guidance literature:

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