Doxycycline hyclate

Base Information

• Chemical Name: Doxycycline hyclate
• CAS No.: 24390-14-5
• Molecular Formula: C22H24N2O8^.HCl
• Molecular Weight: 480.90
• Hs Code.: 29413000
• Mol file: 24390-14-5.mol

Synonyms:Vibramycin (TN);Doxycycline hyclate (USP);(2Z,4S,4aR,5S,5aR,6R,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrate; dihydrochloride;Doxycycline hydrochloride hemiethanolate hemihydrate;DOXY;Doryx (TN);Doryx;Doxycycline Hcl;Dipivefrin HCl;

Chemical Property of Doxycycline hyclate

Chemical Property:

• Appearance/Colour: yellow crystallien powder
• Melting Point: 206-209?C (dec.)
• Boiling Point: 685.2 °C at 760 mmHg
• Flash Point: 368.2 °C
• PSA: 392.70000
• LogP: 2.24370
• Storage Temp.: Store at +4°C
• Solubility.: H2O: soluble50mg/mL
• Water Solubility.: Soluble in water to 50mg/ml. May require warming.Soluble in water, methanol. Sparingly soluble in ethanol. Insoluble in chlorofo

Purity/Quality:

99% ^*data from raw suppliers

Doxycycline Hyclate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: Doxycycline Hyclate is the hyclate salt form of doxycycline, is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix metalloproteinase-8 (MMP-8) and MMP-13 over MMP-1 with 50, 60, and 5% inhibition, respectively, when used at a concentration of 30 μM. It can be used as a regulator for inducible gene expression systems where expression depends on either the presence (Tet-On) or absence (Tet-Off) of doxycycline. Formulations containing doxycycline have been used in the treatment of bacterial infections and the prevention of malaria.
• Uses: Doxycycline hyclate is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is used in the treatment of chlamydia, rickettsia, mycoplasma and some spirochete infections. It is also used to inhibit matrix metalloproteinases at subantimicrobial doses. Inhibits matrix metalloproteinases at subantimicrobial doses.