n-(2-Amino-4,5-dichlorophenyl)benzenesulfonamide

Base Information

• Chemical Name: n-(2-Amino-4,5-dichlorophenyl)benzenesulfonamide
• CAS No.: 91961-96-5
• Molecular Formula: C₁₂H₁₀Cl₂N₂O₂S
• Molecular Weight: 317.196
• NSC Number: 128944
• DSSTox Substance ID: DTXSID50299260
• Wikidata: Q82041530
• Mol file: 91961-96-5.mol

Synonyms:91961-96-5;n-(2-amino-4,5-dichlorophenyl)benzenesulfonamide;NSC128944;DTXSID50299260;NSC-128944

Chemical Property of n-(2-Amino-4,5-dichlorophenyl)benzenesulfonamide

Chemical Property:

• Vapor Pressure: 1.97E-09mmHg at 25°C
• Boiling Point: 481.5°Cat760mmHg
• Flash Point: 245°C
• Density: 1.549g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 315.9840041
• Heavy Atom Count: 19
• Complexity: 393

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)S(=O)(=O)NC2=CC(=C(C=C2N)Cl)Cl

Technology Process of n-(2-Amino-4,5-dichlorophenyl)benzenesulfonamide

There total 4 articles about n-(2-Amino-4,5-dichlorophenyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,5-Dichlor-2-nitro-1-benzolsulfonylamino-benzol (1596-36-7) → 2'-amino-4',5'-dichloro-benzenesulfonanilide (91961-96-5)

Guidance literature:

With hydrogenchloride; tin; In acetic acid; Heating;

DOI:10.1021/jm00341a030

Reference yield:

benzenesulfonic acid-(3,4-dichloro-anilide) (91498-91-8) → 2'-amino-4',5'-dichloro-benzenesulfonanilide (91961-96-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NO₂/HNO₃ / -15 - -5 °C

2: Sn, aq. HCl / acetic acid / Heating

With hydrogenchloride; tin; nitric acid; Nitrogen dioxide; In acetic acid;

DOI:10.1021/jm00341a030

Reference yield:

benzenesulfonyl chloride (98-09-9) → 2'-amino-4',5'-dichloro-benzenesulfonanilide (91961-96-5)

Guidance literature:

Multi-step reaction with 3 steps

1: Py

2: NO₂/HNO₃ / -15 - -5 °C

3: Sn, aq. HCl / acetic acid / Heating

With pyridine; hydrogenchloride; tin; nitric acid; Nitrogen dioxide; In acetic acid;

DOI:10.1021/jm00341a030

upstream raw materials:

4,5-Dichlor-2-nitro-1-benzolsulfonylamino-benzol

benzenesulfonic acid-(3,4-dichloro-anilide)

benzenesulfonyl chloride

m,p-dichloroaniline

Downstream raw materials:

Bernsteinsaeure-mono-<4.5-dichlor-2-benzolsulfonylamino-anilid>

4.5-Dichlor-2-benzolsulfonylamino-1-p-toluolsulfonylamino-benzol