Ethyl 5-(2-bromoacetyl)-2-(phenylmethoxy)benzoate

Base Information

Chemical Name:Ethyl 5-(2-bromoacetyl)-2-(phenylmethoxy)benzoate
CAS No.:56443-71-1
Molecular Formula:C18H17BrO4
Molecular Weight:377.235
Hs Code.:
DSSTox Substance ID:DTXSID001235353

Synonyms:56443-71-1;Ethyl 5-(2-bromoacetyl)-2-(phenylmethoxy)benzoate;SCHEMBL11750017;DTXSID001235353;Ethyl 2-(benzyloxy)-5-(2-bromoacetyl)benzoate

Suppliers and Price of Ethyl 5-(2-bromoacetyl)-2-(phenylmethoxy)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethyl 5-(2-bromoacetyl)-2-(phenylmethoxy)benzoate

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:376.03102
Heavy Atom Count:23
Complexity:393

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=C(C=CC(=C1)C(=O)CBr)OCC2=CC=CC=C2

Technology Process of Ethyl 5-(2-bromoacetyl)-2-(phenylmethoxy)benzoate

There total 3 articles about Ethyl 5-(2-bromoacetyl)-2-(phenylmethoxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 60561-28-6
ethyl 5-acetyl-2-(benzyloxy)benzoate

: 56443-71-1
ethyl 2-(bezyloxy)-5-(2-bromoacetyl)benzoate

: 2-Benzyloxy-5-(2,2-dibromo-acetyl)-benzoic acid ethyl ester

Guidance literature:: With bromine; potassium carbonate; In chloroform; at 0 ℃;
DOI:10.1021/jm00379a004

Reference yield:

: 16475-93-7
5-acetyl-2-hydroxybenzoic acid ethyl ester

: 56443-71-1
ethyl 2-(bezyloxy)-5-(2-bromoacetyl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / K₂CO₃ / dimethylsulfoxide / 5 h / 75 °C

2: 75 percent / K₂CO₃, Br₂ / CHCl₃ / 0 °C

With bromine; potassium carbonate; In chloroform; dimethyl sulfoxide;
DOI:10.1021/jm00379a004

Reference yield:

: 100-44-7
benzyl chloride

: 56443-71-1
ethyl 2-(bezyloxy)-5-(2-bromoacetyl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / K₂CO₃ / dimethylsulfoxide / 5 h / 75 °C

2: 75 percent / K₂CO₃, Br₂ / CHCl₃ / 0 °C

With bromine; potassium carbonate; In chloroform; dimethyl sulfoxide;
DOI:10.1021/jm00379a004