Ethyl 5-acetyl-2-benzyloxybenzoate

Base Information

Chemical Name:Ethyl 5-acetyl-2-benzyloxybenzoate
CAS No.:60561-28-6
Molecular Formula:C18H18 O4
Molecular Weight:298.339
Hs Code.:2918990090
European Community (EC) Number:262-297-5
UNII:63X33E9URK
DSSTox Substance ID:DTXSID50209364
Nikkaji Number:J236.361E
Wikidata:Q83083635
Mol file:60561-28-6.mol

Synonyms:Ethyl 5-acetyl-2-benzyloxybenzoate;60561-28-6;ethyl 5-acetyl-2-phenylmethoxybenzoate;EINECS 262-297-5;Benzoic acid, 5-acetyl-2-(phenylmethoxy)-, ethyl ester;ethyl 5-acetyl-2-(benzyloxy)benzoate;SCHEMBL966146;63X33E9URK;DTXSID50209364;5-Acetyl-2-benzyloxy benzoic ethyl ester;Ethyl 5-acetyl-2-(phenylmethoxy)benzoate;5-Acetyl-2-benzyloxy-benzoic acid ethyl ester;5-Acetyl-2-(benzyloxy)benzoic acid ethyl ester;5-Acetyl-2-(phenylmethoxy)benzoic acid ethyl ester

Suppliers and Price of Ethyl 5-acetyl-2-benzyloxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethyl 5-acetyl-2-benzyloxybenzoate

Chemical Property:

Vapor Pressure:1.9E-08mmHg at 25°C
Boiling Point:454.5°C at 760 mmHg
Flash Point:200.8°C
PSA：52.60000
Density:1.147g/cm³
LogP:3.64490
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:298.12050905
Heavy Atom Count:22
Complexity:373

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C=CC(=C1)C(=O)C)OCC2=CC=CC=C2

Technology Process of Ethyl 5-acetyl-2-benzyloxybenzoate

There total 1 articles about Ethyl 5-acetyl-2-benzyloxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 16475-93-7
5-acetyl-2-hydroxybenzoic acid ethyl ester

: 100-44-7
benzyl chloride

: 60561-28-6
ethyl 5-acetyl-2-(benzyloxy)benzoate

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 75 ℃; for 5h;
DOI:10.1021/jm00379a004

Reference yield: 75.0%

: 60561-28-6
ethyl 5-acetyl-2-(benzyloxy)benzoate

: 56443-71-1
ethyl 2-(bezyloxy)-5-(2-bromoacetyl)benzoate

: 2-Benzyloxy-5-(2,2-dibromo-acetyl)-benzoic acid ethyl ester

Guidance literature:: With bromine; potassium carbonate; In chloroform; at 0 ℃;
DOI:10.1021/jm00379a004

Reference yield:

: 60561-28-6
ethyl 5-acetyl-2-(benzyloxy)benzoate

: 92900-94-2
4-[2-(2-Diethylamino-6,7-dimethoxy-quinazolin-4-ylamino)-1-hydroxy-ethyl]-2-hydroxymethyl-phenol; hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: 75 percent / K₂CO₃, Br₂ / CHCl₃ / 0 °C

2: 93 percent / NaN₃ / acetone; H₂O

3: 78 percent / LiAlH₄ / tetrahydrofuran / 3 h / Heating

4: 81 percent / ethanol / 60 h / 100 °C

5: 59 percent / H₂ / 5percent Pd/C / methanol

With lithium aluminium tetrahydride; sodium azide; hydrogen; bromine; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; chloroform; water; acetone;
DOI:10.1021/jm00379a004