1,7,8,9-Tetrahydropyrano[2,3-g]indole-2-carboxylic acid

Base Information

Chemical Name:1,7,8,9-Tetrahydropyrano[2,3-g]indole-2-carboxylic acid
CAS No.:81257-90-1
Molecular Formula:C12H11NO3
Molecular Weight:217.2206
Hs Code.:
DSSTox Substance ID:DTXSID10230992
Wikidata:Q83111790

Synonyms:81257-90-1;1,7,8,9-tetrahydropyrano[2,3-g]indole-2-carboxylic acid;1,7,8,9-Tetrahydropyrano(2,3-g)indole-2-carboxylic acid;Pyrano(2,3-g)indole-2-carboxylic acid, 1,7,8,9-tetrahydro-;Acide 7,8,9-trihydro-pyranno(2,3-g)indole-2-carboxylique [French];Acide 7,8,9-trihydro-pyranno(2,3-g)indole-2-carboxylique;SCHEMBL4825508;DTXSID10230992;DJJRKYNKJQAPHU-UHFFFAOYSA-N;LS-127364;7,8-Dihydro9H-pyrano[2,3-g]indole-2-carboxylic acid;7,8-dihydro-9H-pyrano[2,3 g]indole-2-carboxylic acid;7,8-Dihydro-9H-pyrano[2,3-g]indole-2-carboxylic acid

Suppliers and Price of 1,7,8,9-Tetrahydropyrano[2,3-g]indole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1,7,8,9-Tetrahydropyrano[2,3-g]indole-2-carboxylic acid

Chemical Property:

Vapor Pressure:5.14E-11mmHg at 25°C
Boiling Point:504.9°Cat760mmHg
Flash Point:259.2°C
Density:1.426g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:294

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=CC3=C2NC(=C3)C(=O)O)OC1

Technology Process of 1,7,8,9-Tetrahydropyrano[2,3-g]indole-2-carboxylic acid

There total 5 articles about 1,7,8,9-Tetrahydropyrano[2,3-g]indole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 81257-87-6
tetrahydro-1,7,8,9 pyranno<2,3-g>indolecarboxylate-2 de methyle

: 81257-90-1
acide tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

Guidance literature:: With hydrogenchloride; potassium hydroxide; water; 1) reflux, 3.5 h; 2) 0 deg C;
DOI:10.1139/v82-298

Reference yield: 83.0%

: 81257-90-1
acide tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

Guidance literature:

Reference yield:

: 55745-97-6
3,4-dihydro-2H-1-benzopyran-6-carbaldehyde

: 81257-90-1
acide tetrahydro-1,7,8,9-pyranno<2,3-g>indolecarboxylique-2

Guidance literature:: Multi-step reaction with 3 steps

1: Na / methanol / 6 h / 0 °C

2: 42 percent / N₂ / xylene / 5 h / Heating

3: 83 percent / 1) KOH, H₂O; 2) 5 N HCl / 1) reflux, 3.5 h; 2) 0 deg C

With hydrogenchloride; potassium hydroxide; nitrogen; water; sodium; In methanol; xylene;
DOI:10.1139/v82-298