1H-Pyrimido[4,5-b]indol-2-amine, 4-phenyl-

Base Information

Chemical Name:1H-Pyrimido[4,5-b]indol-2-amine, 4-phenyl-
CAS No.:56807-24-0
Molecular Formula:C16H12N4
Molecular Weight:260.29300
Hs Code.:
DSSTox Substance ID:DTXSID00481895

Synonyms:1H-Pyrimido[4,5-b]indol-2-amine, 4-phenyl-;56807-24-0;DTXSID00481895;2-amino-4-phenyl-9h-pyrimido[4,5-b]indole

Suppliers and Price of 1H-Pyrimido[4,5-b]indol-2-amine, 4-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 1H-Pyrimido[4,5-b]indol-2-amine, 4-phenyl-

Chemical Property:

Boiling Point:596.7±42.0 °C(Predicted)
PSA：68.32000
Density:1.369±0.06 g/cm3(Predicted)
LogP:3.29040
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:260.106196400
Heavy Atom Count:20
Complexity:341

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C3C4=CC=CC=C4NC3=NC(=N2)N

Technology Process of 1H-Pyrimido[4,5-b]indol-2-amine, 4-phenyl-

There total 4 articles about 1H-Pyrimido[4,5-b]indol-2-amine, 4-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 64-17-5
ethanol

: 2-nitramino-4-phenyl-9H-pyrimido[4,5-b]indole

: 56807-24-0
2-amino-4-phenyl-9H-pyrimido[4,5-b]indole

: 524047-81-2
4-phenyl-9H-pyrimido[4,5-b]indole

: 2-ethoxy-4-phenyl-9H-pyrimido[4,5-b]indole

Guidance literature:: With hydrogen; palladium on activated charcoal; at 35 - 40 ℃;
DOI:10.1023/A:1021688616234

Reference yield: 29.0%

: 524047-80-1
2-chloro-4-phenyl-9H-pyrimido[4,5-b]indole

: 56807-24-0
2-amino-4-phenyl-9H-pyrimido[4,5-b]indole

: 524047-81-2
4-phenyl-9H-pyrimido[4,5-b]indole

Guidance literature:: With hydrazine hydrate; In dimethyl sulfoxide; at 100 - 110 ℃; for 16h;
DOI:10.1023/A:1021688616234

Reference yield:

: 56807-28-4
2-oxo-4-phenyl-2,3-dihydro-9H-pyrimido[4,5-b]indole

: 56807-24-0
2-amino-4-phenyl-9H-pyrimido[4,5-b]indole

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / POCl₃; DMF / 5 h / 60 °C

2: 29 percent / N₂H₄*H₂O / dimethylsulfoxide / 16 h / 100 - 110 °C

With hydrazine hydrate; N,N-dimethyl-formamide; trichlorophosphate; In dimethyl sulfoxide;
DOI:10.1023/A:1021688616234