5-(Benzyloxy)-3-bromo-1H-indole

Base Information

Chemical Name:5-(Benzyloxy)-3-bromo-1H-indole
CAS No.:569337-39-9
Molecular Formula:C15H12BrNO
Molecular Weight:302.16600
Hs Code.:2933990090
European Community (EC) Number:892-015-1
DSSTox Substance ID:DTXSID20477452
Nikkaji Number:J1.897.273E
Mol file:569337-39-9.mol

Synonyms:5-(BENZYLOXY)-3-BROMO-1H-INDOLE;569337-39-9;3-bromo-5-phenylmethoxy-1H-indole;3-bromo-5-benzyloxyindole;1H-Indole, 3-bromo-5-(phenylmethoxy)-;SCHEMBL6081390;DTXSID20477452;RGXOJKXWRRGKJN-UHFFFAOYSA-N;MFCD11110952;CS-0270093;FT-0703437;EN300-1275501

Suppliers and Price of 5-(Benzyloxy)-3-bromo-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(Benzyloxy)-3-bromo-1H-indole 97%
1g
$ 356.00

Crysdot
5-(Benzyloxy)-3-bromo-1H-indole 97%
5g
$ 1069.00

Chemenu
5-(benzyloxy)-3-bromo-1H-indole 95%+
5g
$ 1007.00

Chemenu
5-(benzyloxy)-3-bromo-1H-indole 95%+
1g
$ 336.00

Total 10 raw suppliers

Chemical Property of 5-(Benzyloxy)-3-bromo-1H-indole

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:89-92 °C
Boiling Point:459.023oC at 760 mmHg
PKA:14.96±0.30(Predicted)
Flash Point:231.409oC
PSA：25.02000
Density:1.49g/cm3
LogP:4.50940
Storage Temp.:2-8°C
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:301.01023
Heavy Atom Count:18
Complexity:267

Purity/Quality:

98% ^*data from raw suppliers

5-(Benzyloxy)-3-bromo-1H-indole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC3=C(C=C2)NC=C3Br

Technology Process of 5-(Benzyloxy)-3-bromo-1H-indole

There total 1 articles about 5-(Benzyloxy)-3-bromo-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1215-59-4
5-benzyloxy-1H-indole

: 569337-39-9
3-bromo-5-benzyloxyindole

Guidance literature:: With bromine; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(03)00837-2

Reference yield: 69.0%

: 109-97-7,30604-81-0
pyrrole

: 569337-39-9
3-bromo-5-benzyloxyindole

: 569337-40-2
5-benzyloxy-2-(1H-pyrrol-2-yl)-1H-indole

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/S0040-4039(03)00837-2

Reference yield:

: 569337-39-9
3-bromo-5-benzyloxyindole

: 8-benzyloxy-11H-3a,5,11-triaza-benzo[a]trindene-4,6-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 69 percent / TFA / CH₂Cl₂ / 20 °C

2: 68 percent / SnCl₂ / toluene / Heating

3: 35 percent / Pd black / nitrobenzene / 200 °C

With trifluoroacetic acid; tin(ll) chloride; palladium; In dichloromethane; nitrobenzene; toluene; 2: Michael addition;
DOI:10.1016/S0040-4039(03)00837-2