2-methyl-1,3-diphenylisothiourea

Base Information

• Chemical Name: 2-methyl-1,3-diphenylisothiourea
• CAS No.: 5416-30-8
• Molecular Formula: C14H14N2S
• Molecular Weight: 242.345
• Mol file: 5416-30-8.mol

Synonyms:S-Methyl N,N-diphenyl thiopseudourea;Pseudourea, 2-methyl-1, 3-diphenyl-2-thio-;1-methylsulfanyl-N,N-diphenyl-methanimidamide;Pseudourea, 1,3-diphenyl-2-methyl-2-thio-;

Chemical Property of 2-methyl-1,3-diphenylisothiourea

Chemical Property:

• Vapor Pressure: 8.88E-06mmHg at 25°C
• Refractive Index: 1.59
• Boiling Point: 373.6°Cat760mmHg
• Flash Point: 179.7°C
• Density: 1.08g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-methyl-1,3-diphenylisothiourea

There total 12 articles about 2-methyl-1,3-diphenylisothiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

S-methyl-N,N'-diphenyl-isothiourea; hydriodide (60006-92-0) → N,N'-diphenyl-S-methyl isothiourea (5416-30-8)

Guidance literature:

With ammonium hydroxide;

DOI:10.1055/s-1980-28927

Reference yield: 62.0%

N,N-diphenylthiourea (102-08-9) + methyl iodide (74-88-4) → N,N'-diphenyl-S-methyl isothiourea (5416-30-8)

Guidance literature:

N,N-diphenylthiourea; With N-<(trimethylsiloxy)methyl>dimethylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

methyl iodide; In dichloromethane; at 20 ℃; for 2.25h; Inert atmosphere;

DOI:10.1134/S1070428019110198

Reference yield:

N,N-diphenylthiourea (102-08-9) + methyl iodide (74-88-4) → N,N'-diphenyl-S-methyl isothiourea (5416-30-8)

Guidance literature:

With potassium carbonate; In acetone;

DOI:10.1021/ol050728q

upstream raw materials:

dimethyl sulfate

N,N-diphenylthiourea

methyl iodide

1,1-diphenylthiourea

Downstream raw materials:

6-methyl-3-phenyl-2-phenylimino-2,3-dihydro-[1,3]oxazin-4-one

2-(phenylamino)-3-(phenyl)-4(3H)-quinazolinone

3-phenyl-2-(phenylimino)-1,3-thiazolidin-4-one

1-methyl-1,3-diphenylurea

Refernces

• 1、 Hamilton, Sean K.,Wilkinson, Doug E.,Hamilton, Gregory S.,Wu, Yong-Qian. "Microwave-assisted synthesis of N,N′-diaryl cyanoguanidines". . p. 2429 - 2431. Retrieved 2007/10/03.