Diethyl trans-3-Hexenedioate

Base Information

• Chemical Name: Diethyl trans-3-Hexenedioate
• CAS No.: 57042-08-7
• Molecular Formula: C10H16O4
• Molecular Weight: 200.235
• Mol file: 57042-08-7.mol

Synonyms:

Chemical Property of Diethyl trans-3-Hexenedioate

Chemical Property:

• Refractive Index: 1.4420-1.4450
• Boiling Point: 133-135 °C(Press: 14 Torr)
• PSA: 52.60000
• Density: 1.031±0.06 g/cm3(Predicted)
• LogP: 1.44900

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diethyl trans-3-Hexenedioate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Diethyl trans-3-Hexenedioate

There total 9 articles about Diethyl trans-3-Hexenedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethanol (64-17-5) + (E)-3-hexene-1,6-dioic acid (29311-53-3) → Diethyl trans-hex-3-enedioate (57042-08-7)

Guidance literature:

With sulfuric acid; In benzene; at 90 ℃; for 48h;

Reference yield:

trans-β-hydromuconic acid dichloride (58823-57-7) + ethanol (64-17-5) → Diethyl trans-hex-3-enedioate (57042-08-7)

Guidance literature:

With triethylamine; at 20 ℃; for 1.5h; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.10.021

Reference yield:

ethyl trans-β-chloroacrylate (16491-00-2) → Diethyl trans-hex-3-enedioate (57042-08-7) + cis-3-Hexendicarbonsaeurediaethylester (875758-56-8)

Guidance literature:

With water; nickel dichloride; zinc; In pyridine; at 20 ℃; for 1h; Title compound not separated from byproducts;

DOI:10.1246/cl.2000.236

upstream raw materials:

ethanol

trans-1,4-dicyano-2-butene

(E)-3-hexene-1,6-dioic acid

2-hexenedinitrile

Downstream raw materials:

3-oxo-propionic acid ethyl ester

diethyl adipate

hexamethonium bromide

trans-4-octene-1,8-dioic acid

Refernces

• 1、 Edvinsson, Sofie,Johansson, Susanne,Larsson, Andreas. "An efficient procedure for the synthesis of formylacetic esters". . p. 6819 - 6821. Retrieved 2013/01/15.
• 2、 Kotora, Martin,Matsumura, Hiroshi,Takahashi, Tamotsu. "Ni-catalyzed homocoupling of 3-halopropenoates in the presence of water: Formation of hexenedioates". . p. 236 - 237. Retrieved 2007/10/03.