Ethyl 4-[(quinolin-3-ylmethyl)amino]benzoate

Base Information

Chemical Name:Ethyl 4-[(quinolin-3-ylmethyl)amino]benzoate
CAS No.:25927-76-8
Molecular Formula:C19H18 N2 O2
Molecular Weight:306.364
Hs Code.:
NSC Number:131154
DSSTox Substance ID:DTXSID90299522
Wikidata:Q82041977

Synonyms:25927-76-8;ethyl 4-[(quinolin-3-ylmethyl)amino]benzoate;NSC131154;DTXSID90299522;NSC-131154;FT-0750471

Suppliers and Price of Ethyl 4-[(quinolin-3-ylmethyl)amino]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethyl 4-[(quinolin-3-ylmethyl)amino]benzoate

Chemical Property:

Vapor Pressure:1.1E-09mmHg at 25°C
Boiling Point:488.3°Cat760mmHg
Flash Point:249.1°C
Density:1.218g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:306.136827821
Heavy Atom Count:23
Complexity:380

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=C(C=C1)NCC2=CC3=CC=CC=C3N=C2

Technology Process of Ethyl 4-[(quinolin-3-ylmethyl)amino]benzoate

There total 4 articles about Ethyl 4-[(quinolin-3-ylmethyl)amino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.4%

: 25927-75-7
4-quinolin-3-ylmethyleneamino-benzoic acid ethyl ester

: 25927-76-8
ethyl 4-{[(quinoline-3-yl)methyl]amino}benzoate

Guidance literature:: With sodium tetrahydroborate; In methanol;
DOI:10.1002/ardp.19803130209

Reference yield:

: 13669-42-6
3-quinolylcarboxaldehyde

: 25927-76-8
ethyl 4-{[(quinoline-3-yl)methyl]amino}benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 70.2 percent / benzene / 6 h / Heating

2: 60.4 percent / NaBH₄ / methanol

With sodium tetrahydroborate; In methanol; benzene;
DOI:10.1002/ardp.19803130209

Reference yield:

: 94-09-7
p-aminoethylbenzoate

: 25927-76-8
ethyl 4-{[(quinoline-3-yl)methyl]amino}benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 70.2 percent / benzene / 6 h / Heating

2: 60.4 percent / NaBH₄ / methanol

With sodium tetrahydroborate; In methanol; benzene;
DOI:10.1002/ardp.19803130209