2(1H)-Pyridinone, 1-(1-(4-chlorobenzoyl)-2-(4-fluorophenyl)ethenyl)-

Base Information

Chemical Name:2(1H)-Pyridinone, 1-(1-(4-chlorobenzoyl)-2-(4-fluorophenyl)ethenyl)-
CAS No.:104941-02-8
Molecular Formula:C20H13 Cl F N O2
Molecular Weight:353.7741
Hs Code.:
ChEMBL ID:CHEMBL284170
Mol file:104941-02-8.mol

Synonyms:104941-02-8;2(1H)-Pyridinone, 1-(1-(4-chlorobenzoyl)-2-(4-fluorophenyl)ethenyl)-;2(1H)-Pyridinone, 1-[1-(4-chlorobenzoyl)-2-(4-fluorophenyl)ethenyl]-;CHEMBL284170;1-[(Z)-1-(4-chlorobenzoyl)-2-(4-fluorophenyl)vinyl]pyridin-2-one

Suppliers and Price of 2(1H)-Pyridinone, 1-(1-(4-chlorobenzoyl)-2-(4-fluorophenyl)ethenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2(1H)-Pyridinone, 1-(1-(4-chlorobenzoyl)-2-(4-fluorophenyl)ethenyl)-

Chemical Property:

Vapor Pressure:6.67E-12mmHg at 25°C
Boiling Point:544.2°Cat760mmHg
Flash Point:282.9°C
Density:1.366g/cm³
XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:353.0618845
Heavy Atom Count:25
Complexity:597

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=O)N(C=C1)C(=CC2=CC=C(C=C2)F)C(=O)C3=CC=C(C=C3)Cl
Isomeric SMILES:C1=CC(=O)N(C=C1)/C(=C\C2=CC=C(C=C2)F)/C(=O)C3=CC=C(C=C3)Cl

Technology Process of 2(1H)-Pyridinone, 1-(1-(4-chlorobenzoyl)-2-(4-fluorophenyl)ethenyl)-

There total 3 articles about 2(1H)-Pyridinone, 1-(1-(4-chlorobenzoyl)-2-(4-fluorophenyl)ethenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 459-57-4
4-fluorobenzaldehyde

: 108664-55-7
1-[2-(4-Chloro-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one

: 104941-02-8
4'-chloro-4-fluoro-α-(2-oxo-1,2-dihydropyridin-1-yl)-chalcone

Guidance literature:: With piperidine; acetic acid; In toluene; for 2h; Heating;
DOI:10.1021/jm00391a037

Reference yield:

: 142-08-5,1199357-22-6
2-Pyridone

: 104941-02-8
4'-chloro-4-fluoro-α-(2-oxo-1,2-dihydropyridin-1-yl)-chalcone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.2 g / KOH / dimethylformamide / 0.5 h / Ambient temperature

2: 73 percent / AcOH, piperidine / toluene / 2 h / Heating

With piperidine; potassium hydroxide; acetic acid; In N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00391a037

Reference yield:

: 536-38-9
4-chlorobenzoylmethyl bromide

: 104941-02-8
4'-chloro-4-fluoro-α-(2-oxo-1,2-dihydropyridin-1-yl)-chalcone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.2 g / KOH / dimethylformamide / 0.5 h / Ambient temperature

2: 73 percent / AcOH, piperidine / toluene / 2 h / Heating

With piperidine; potassium hydroxide; acetic acid; In N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00391a037