2-hydroxy-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide

Base Information

• Chemical Name: 2-hydroxy-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide
• CAS No.: 19015-16-8
• Molecular Formula: C12H11N3O2
• Molecular Weight: 229.238
• Mol file: 19015-16-8.mol

Synonyms:HMS1677M17;HMS2689H21;Pyrrol-2-carboxaldehyd-(2-hydroxy-benzoyl-hydrazon);

Chemical Property of 2-hydroxy-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide

Chemical Property:

• Melting Point: 222-223 °C (decomp)
• Boiling Point: 375.7°Cat760mmHg
• PKA: 8.48±0.30(Predicted)
• Flash Point: 181°C
• PSA: 77.21000
• Density: 1.29g/cm³
• LogP: 1.50990

Purity/Quality:

2-hydroxy-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-hydroxy-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide

There total 2 articles about 2-hydroxy-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.46%

2-pyrrole aldehyde (1003-29-8,254729-95-8) + 2-Hydroxybenzoylhydrazine (936-02-7) → 2-hydroxybenzoic acid N'-(1H-pyrrol-2-ylmethylene)hydrazide (19015-16-8)

Guidance literature:

In water; for 2h; Cooling with ice; Green chemistry;

DOI:10.1016/j.molstruc.2015.07.005

Reference yield:

→ 2-hydroxybenzoic acid N'-(1H-pyrrol-2-ylmethylene)hydrazide (19015-16-8)

Guidance literature:

Pyrrol-2-carboxaldehyd, 2-Hydroxy-benzoyl-hydrazin/A., Δ;

Reference yield: 63.0%

2-hydroxybenzoic acid N'-(1H-pyrrol-2-ylmethylene)hydrazide (19015-16-8) + cobalt(II) chloride (7646-79-9,14543-09-0,16413-89-1) → [Co((C6H4OH)CONNCH(C4H3NH))2]

Guidance literature:

In ethanol; solutions mixed with stirring; refluxed for 2 h; cooled to room temp.; filtered; reduced to nearly half of volume; left standing overnight at room temp.; filtered; washed (ethanol, then ether); dried; crystd. (aq. ethanol); elem. anal.;

DOI:10.1081/SIM-120003793

upstream raw materials:

2-pyrrole aldehyde

2-Hydroxybenzoylhydrazine