4-Acridinecarboxamide, 7-chloro-N-(2-(dimethylamino)ethyl)-

Base Information

Chemical Name:4-Acridinecarboxamide, 7-chloro-N-(2-(dimethylamino)ethyl)-
CAS No.:106626-80-6
Molecular Formula:C₁₈H₁₈ClN₃O
Molecular Weight:327.813
Hs Code.:
DSSTox Substance ID:DTXSID00147702
Nikkaji Number:J848.005B
Wikidata:Q83013092
ChEMBL ID:CHEMBL57949

Synonyms:Cl(N-(2-(dimethylamino)ethyl)acridine-4-carboxamide);Cl-DACA

Suppliers and Price of 4-Acridinecarboxamide, 7-chloro-N-(2-(dimethylamino)ethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Acridinecarboxamide, 7-chloro-N-(2-(dimethylamino)ethyl)-

Chemical Property:

Vapor Pressure:5.82E-13mmHg at 25°C
Boiling Point:569°Cat760mmHg
Flash Point:297.9°C
PSA：48.72000
Density:1.261g/cm³
LogP:3.90760
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:327.1138399
Heavy Atom Count:23
Complexity:417

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCNC(=O)C1=CC=CC2=CC3=C(C=CC(=C3)Cl)N=C21

Technology Process of 4-Acridinecarboxamide, 7-chloro-N-(2-(dimethylamino)ethyl)-

There total 2 articles about 4-Acridinecarboxamide, 7-chloro-N-(2-(dimethylamino)ethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24782-71-6
9-Oxo-7-chloracridon-4-carbonsaeure

: 106626-80-6
7-Chloro-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Et₃N, 2.) Al(Hg), 3.) 12N HCl, FeCl₃

2: 1.) 1,1'-carbonyldiimidazole / 1.) DMF, 20 deg C, 2.) DMF, 0 deg C, 5 min

With hydrogenchloride; aluminum amalgam; iron(III) chloride; triethylamine; 1,1'-carbonyldiimidazole;
DOI:10.1021/jm00387a014

Reference yield:

: 32602-24-7
7-chloroacridine-4-carboxylic acid

: 108-00-9
N,N-dimethylethylenediamine

: 106626-80-6
7-Chloro-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

Guidance literature:: With 1,1'-carbonyldiimidazole; Yield given. Multistep reaction; 1.) DMF, 20 deg C, 2.) DMF, 0 deg C, 5 min;
DOI:10.1021/jm00387a014