Technology Process of 4-Oxazolecarboxylic acid, 5-(2-aminophenyl)-2-phenyl-, ethyl ester
There total 4 articles about 4-Oxazolecarboxylic acid, 5-(2-aminophenyl)-2-phenyl-, ethyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
for 1h;
under 2585.81 Torr;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 80 percent / Pd(OAc)2; PPh3; Cs2CO3 / dimethylformamide / 3 h / 140 °C
2: 100 percent / H2 / Pd/C / methanol / 1 h
With
palladium diacetate; hydrogen; caesium carbonate; triphenylphosphine;
palladium on activated charcoal;
In
methanol; N,N-dimethyl-formamide;
1: Heck reaction;
DOI:10.1021/ol0350285
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tert-butyl nitrite; CuCl2 / acetonitrile / 60 - 80 °C
1.2: 83 percent / conc. HCl / acetonitrile; CH2Cl2
2.1: 87 percent / Pd(PPh3)4; aq. K2CO3 / toluene / 1 h / 90 °C
3.1: 80 percent / Pd(OAc)2; PPh3; Cs2CO3 / dimethylformamide / 3 h / 140 °C
4.1: 100 percent / H2 / Pd/C / methanol / 1 h
With
palladium diacetate; tetrakis(triphenylphosphine) palladium(0); tert.-butylnitrite; hydrogen; potassium carbonate; caesium carbonate; triphenylphosphine; copper dichloride;
palladium on activated charcoal;
In
methanol; N,N-dimethyl-formamide; toluene; acetonitrile;
2.1: Suzuki-Miyaura reaction / 3.1: Heck reaction;
DOI:10.1021/ol0350285
