1-(Benzoyloxy)-2-phenyl-1H-indole

Base Information

• Chemical Name: 1-(Benzoyloxy)-2-phenyl-1H-indole
• CAS No.: 58810-39-2
• Molecular Formula: C21H15NO2
• Molecular Weight: 313.356
• DSSTox Substance ID: DTXSID10495620
• Wikidata: Q82343843
• Mol file: 58810-39-2.mol

Synonyms:1-(Benzoyloxy)-2-phenyl-1H-indole;58810-39-2;SCHEMBL5201047;DTXSID10495620

Chemical Property of 1-(Benzoyloxy)-2-phenyl-1H-indole

Chemical Property:

• XLogP3: 5.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 313.110278721
• Heavy Atom Count: 24
• Complexity: 426

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC3=CC=CC=C3N2OC(=O)C4=CC=CC=C4

Technology Process of 1-(Benzoyloxy)-2-phenyl-1H-indole

There total 8 articles about 1-(Benzoyloxy)-2-phenyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-phenyl-N-hydroxyindole (1859-39-8) + benzoyl chloride (98-88-4) → 2-phenyl-1H-indol-1-yl benzoate (58810-39-2)

Guidance literature:

With sodium carbonate; In dichloromethane; for 120h; Ambient temperature;

Reference yield: 45.2%

Quinoline N-oxide (1613-37-2) + 2-phenyl-N-hydroxyindole (1859-39-8) + benzoyl chloride (98-88-4) → 2-phenylisatogen (1969-74-0) + 2-phenyl-1H-indol-1-yl benzoate (58810-39-2) + 1-hydroxy-2-phenyl-3-(2-quinolyl)indole (64968-19-0) + 1-benzoyloxy-2-phenyl-3-(2-quinolyl)indole (64968-18-9)

Guidance literature:

In chloroform; for 4h; Heating;

DOI:10.1248/cpb.29.1827

Reference yield: 27.1%

2-phenyl-N-hydroxyindole (1859-39-8) + benzoyl chloride (98-88-4) → 2-phenylisatogen (1969-74-0) + 2-phenyl-1H-indol-1-yl benzoate (58810-39-2) + 1-hydroxy-2-phenyl-3-(2-quinolyl)indole (64968-19-0) + 1-benzoyloxy-2-phenyl-3-(2-quinolyl)indole (64968-18-9)

Guidance literature:

With Quinoline N-oxide; In chloroform; for 4h; Heating;

DOI:10.1248/cpb.29.1827

upstream raw materials:

Quinoline N-oxide

2-phenyl-N-hydroxyindole

benzoyl chloride

(E)-2-nitrostilbene

Downstream raw materials:

1-benzoyloxy-2-phenyl-3-(2-quinolyl)indole

2-phenyl-1H-indol-3-yl benzoate

1-hydroxy-2-phenyl-3-(2-quinolyl)indole