2-Tridecene-5,7-dione, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,11-bis[(4-methoxyphenyl)meth oxy]-4,4-dimethyl-12-(phenylmethoxy)-, (2E,9R,11R,12R)-

Base Information

Chemical Name:2-Tridecene-5,7-dione, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,11-bis[(4-methoxyphenyl)meth oxy]-4,4-dimethyl-12-(phenylmethoxy)-, (2E,9R,11R,12R)-
CAS No.:588728-61-4
Molecular Formula:C44H62O8Si
Molecular Weight:747.057
Hs Code.:

2-Tridecene-5,7-dione,
9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,11-bis[(4-methoxyphenyl)meth
oxy]-4,4-dimethyl-12-(phenylmethoxy)-, (2E,9R,11R,12R)-

Synonyms:

Suppliers and Price of 2-Tridecene-5,7-dione, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,11-bis[(4-methoxyphenyl)meth oxy]-4,4-dimethyl-12-(phenylmethoxy)-, (2E,9R,11R,12R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Tridecene-5,7-dione, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,11-bis[(4-methoxyphenyl)meth oxy]-4,4-dimethyl-12-(phenylmethoxy)-, (2E,9R,11R,12R)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Tridecene-5,7-dione, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,11-bis[(4-methoxyphenyl)meth oxy]-4,4-dimethyl-12-(phenylmethoxy)-, (2E,9R,11R,12R)-

There total 11 articles about 2-Tridecene-5,7-dione, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,11-bis[(4-methoxyphenyl)meth oxy]-4,4-dimethyl-12-(phenylmethoxy)-, (2E,9R,11R,12R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: (E)-(9R,11R,12R)-12-Benzyloxy-9-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-1,11-bis-(4-methoxy-benzyloxy)-4,4-dimethyl-tridec-2-en-7-one

: 588728-61-4
(E)-(9R,11R,12R)-12-Benzyloxy-9-(tert-butyl-dimethyl-silanyloxy)-1,11-bis-(4-methoxy-benzyloxy)-4,4-dimethyl-tridec-2-ene-5,7-dione

Guidance literature:: With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide; In dichloromethane; for 0.5h;
DOI:10.1021/ol0355332

Reference yield:

: 76352-72-2
methyl 2,2-dimethyl-4-pentenoate

: 588728-61-4
(E)-(9R,11R,12R)-12-Benzyloxy-9-(tert-butyl-dimethyl-silanyloxy)-1,11-bis-(4-methoxy-benzyloxy)-4,4-dimethyl-tridec-2-ene-5,7-dione

Guidance literature:: Multi-step reaction with 5 steps

1.1: 74 percent / N-bromosuccinimide; dibenzoylperoxide / CCl₄ / 2 h / Heating

2.1: NaH / tetrahydrofuran / 6 h / 35 °C

2.2: 6.54 g / PhMgBr / tetrahydrofuran / 1 h / -20 °C

3.1: 99 percent / tetrahydrofuran; diethyl ether / 1 h / -78 °C

4.1: LDA / tetrahydrofuran; hexane / -78 - 20 °C

4.2: 96 percent / tetrahydrofuran; hexane / 0.25 h / -78 °C

5.1: 55 percent / N-methylmorpholine N-oxide; tetrapropyl ammonium perruthenate / CH₂Cl₂ / 0.5 h

With N-Bromosuccinimide; tetrapropylammonium perruthennate; sodium hydride; 4-methylmorpholine N-oxide; lithium diisopropyl amide; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; diethyl ether; hexane; dichloromethane;
DOI:10.1021/ol0355332

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 588728-61-4
(E)-(9R,11R,12R)-12-Benzyloxy-9-(tert-butyl-dimethyl-silanyloxy)-1,11-bis-(4-methoxy-benzyloxy)-4,4-dimethyl-tridec-2-ene-5,7-dione

Guidance literature:: Multi-step reaction with 5 steps

1.1: 86 percent / NaH; dimethylaminopyridine / CH₂Cl₂ / 16 h / Heating

2.1: N-methylmorpholine N-oxide; OsO₄ / tetrahydrofuran; H₂O; propan-2-ol / 6 h / 20 °C

3.1: 0.0297 g / NaIO₄ / tetrahydrofuran; H₂O / 6 h / 20 °C

4.1: LDA / tetrahydrofuran; hexane / -78 - 20 °C

4.2: 96 percent / tetrahydrofuran; hexane / 0.25 h / -78 °C

5.1: 55 percent / N-methylmorpholine N-oxide; tetrapropyl ammonium perruthenate / CH₂Cl₂ / 0.5 h

With dmap; sodium periodate; osmium(VIII) oxide; tetrapropylammonium perruthennate; sodium hydride; 4-methylmorpholine N-oxide; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane; water; isopropyl alcohol;
DOI:10.1021/ol0355332