2-Amino-5-(methylthio)-1,3,4-thiadiazole

Base Information

Chemical Name:2-Amino-5-(methylthio)-1,3,4-thiadiazole
CAS No.:5319-77-7
Molecular Formula:C3H5N3S2
Molecular Weight:147.225
Hs Code.:29349990
European Community (EC) Number:672-510-7
NSC Number:67524
DSSTox Substance ID:DTXSID70201249
Nikkaji Number:J103.226G
Wikidata:Q72439798
ChEMBL ID:CHEMBL174202
Mol file:5319-77-7.mol

Synonyms:5319-77-7;2-Amino-5-(methylthio)-1,3,4-thiadiazole;5-(Methylthio)-1,3,4-thiadiazol-2-amine;1,3,4-Thiadiazol-2-amine, 5-(methylthio)-;5-methylsulfanyl-1,3,4-thiadiazol-2-amine;5-(Methylsulfanyl)-1,3,4-thiadiazol-2-amine;1,3,4-THIADIAZOLE, 2-AMINO-5-(METHYLTHIO)-;2-Amino-5-methylthio-1,3,4-thiadiazole;2-Amino-5-methylmercapto-1,3,4-thiadiazole;NSC 67524;BRN 0118749;MFCD00175752;2-Amino-5-methylthio-1,3,4-thidiazole;4-27-00-08165 (Beilstein Handbook Reference);NSC67524;SCHEMBL750885;CHEMBL174202;DTXSID70201249;CHEBI:194593;GEO-00174;NSC-67524;STK722184;AKOS000112106;PS-4558;5-methylthio-2-amino-1,3,4-thiadiazole;1,4-Thiadiazol-2-amine, 5-(methylthio)-;2-Amino-5-methyl thio-1,3,4-thiadiazole;5-methylsulanyl-1,3,4-thiadiazol-2-amine;LS-150249;1,4-Thiadiazole, 2-amino-5-(methylthio)-;A4801;FT-0611139;EN300-1263664;5-(Methylsulfanyl)-1,3,4-thiadiazol-2-amine #;A870795;2-Amino-5-(methylthio)-1,3,4-thiadiazole, 99%;W-200411;Z18452635;F1386-0088

Suppliers and Price of 2-Amino-5-(methylthio)-1,3,4-thiadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(Methylthio)-1,3,4-thiadiazol-2-amine
2.5g
$ 45.00

SynQuest Laboratories
2-Amino-5-(methylthio)-1,3,4-thiadiazole
25 g
$ 264.00

SynQuest Laboratories
2-Amino-5-(methylthio)-1,3,4-thiadiazole
5 g
$ 116.00

Sigma-Aldrich
2-Amino-5-(methylthio)-1,3,4-thiadiazole 99%
5g
$ 73.60

Medical Isotopes, Inc.
5-(Methylthio)-1,3,4-thiadiazol-2-amine
25 g
$ 2200.00

Matrix Scientific
5-(Methylthio)-1,3,4-thiadiazol-2-amine 97%
10g
$ 588.00

Matrix Scientific
5-(Methylthio)-1,3,4-thiadiazol-2-amine 97%
1g
$ 93.00

Frontier Specialty Chemicals
2-Amino-5-(methylthio)-1,3,4-thiadiazole 99%
5g
$ 127.00

Crysdot
5-(Methylthio)-1,3,4-thiadiazol-2-amine 95+%
5g
$ 58.00

Crysdot
5-(Methylthio)-1,3,4-thiadiazol-2-amine 95+%
10g
$ 105.00

Total 28 raw suppliers

Chemical Property of 2-Amino-5-(methylthio)-1,3,4-thiadiazole

Chemical Property:

Appearance/Colour:Yellowish crystalline powder
Vapor Pressure:0.000369mmHg at 25°C
Melting Point:178-181 °C(lit.)
Refractive Index:1.662
Boiling Point:318.1 °C at 760 mmHg
PKA:3.37±0.10(Predicted)
Flash Point:146.2 °C
PSA：106.07000
Density:1.48 g/cm³
LogP:0.77230
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:146.99248952
Heavy Atom Count:8
Complexity:78.9

Purity/Quality:

97% ^*data from raw suppliers

5-(Methylthio)-1,3,4-thiadiazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/22
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CSC1=NN=C(S1)N
Uses 2-Amino-5-(methylthio)-1,3,4-thiadiazole may be used in the synthesis of 9-methylthio-7,7-dioxo-7,7a-dihydro-5-oxo-7λ6,10-dithia-8,11-diaza-cyclopenta[b] phenantren-6-one by reacting with 4-chloro-2-oxo-2H-chromene-3-sulfonyl chloride.

Technology Process of 2-Amino-5-(methylthio)-1,3,4-thiadiazole

There total 14 articles about 2-Amino-5-(methylthio)-1,3,4-thiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 74-83-9
methyl bromide

: 2349-67-9
2-Amino-5-mercapto-1,3,4-thiadiazole

: 5319-77-7
2-amino-5-methylthio-1,3,4-thiadiazole

Guidance literature:: 2-Amino-5-mercapto-1,3,4-thiadiazole; With potassium hydroxide; In ethanol; for 0.166667h;

methyl bromide; In ethanol; for 2h;
DOI:10.1002/cmdc.201300244