2-(ethoxycarbonyl)pent-4-enoic acid

Base Information

• Chemical Name: 2-(ethoxycarbonyl)pent-4-enoic acid
• CAS No.: 2985-38-8
• Molecular Formula: C8H12 O4
• Molecular Weight: 172.181
• Mol file: 2985-38-8.mol

Synonyms:Malonicacid, allyl-, ethyl ester (7CI); Malonic acid, allyl-, monoethyl ester (8CI);Propanedioic acid, 2-propenyl-, monoethyl ester (9CI); Allylmalonic acidmonoethyl ester; Ethyl allylmalonate; NSC 51128

Chemical Property of 2-(ethoxycarbonyl)pent-4-enoic acid

Chemical Property:

• Vapor Pressure: 0.00317mmHg at 25°C
• Boiling Point: 262.7°Cat760mmHg
• Flash Point: 100.7°C
• Density: 1.116g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(ethoxycarbonyl)pent-4-enoic acid

There total 1 articles about 2-(ethoxycarbonyl)pent-4-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.9%

allyl bromide (106-95-6) + diethyl malonate (105-53-3) → 2-(ethoxycarbonyl)-4-pentenoic acid (2985-38-8) + diallylmalonic acid diethyl ester (3195-24-2)

Guidance literature:

diethyl malonate; With sodium ethanolate; In ethanol;

allyl bromide; In ethanol; for 3h; Heating;

DOI:10.1016/j.jfluchem.2004.03.012

Reference yield: 97.0%

2-(ethoxycarbonyl)-4-pentenoic acid (2985-38-8) → ethyl 4-pentenoate (1968-40-7)

Guidance literature:

With 1H-imidazole; In neat (no solvent); at 124 ℃; for 0.0666667h; Microwave irradiation;

DOI:10.1016/j.tet.2015.09.012

Reference yield: 70.0%

2-(ethoxycarbonyl)-4-pentenoic acid (2985-38-8) + (R)-1-phenyl-ethyl-amine (3886-69-9) → 2-((R)-1-Phenyl-ethylcarbamoyl)-pent-4-enoic acid ethyl ester

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; 1.) 0 deg C, 2 h, 2.) room temperature, 4 h;

DOI:10.1016/S0040-4020(99)00084-8

upstream raw materials:

allyl bromide

diethyl malonate

Downstream raw materials:

C₂₇H₂₇N₂O₃P

C₂₂H₂₇NO₇

ethyl 4-pentenoate