2-Piperazin-1-ylmethyl-1H-benzoimidazole

Base Information

Chemical Name:2-Piperazin-1-ylmethyl-1H-benzoimidazole
CAS No.:59052-85-6
Molecular Formula:C12H16N4
Molecular Weight:216.28200
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50371898
Wikidata:Q82159418
Mol file:59052-85-6.mol

Synonyms:2-Piperazin-1-ylmethyl-1H-benzoimidazole;59052-85-6;2-(piperazin-1-ylmethyl)-1H-benzimidazole;2-(Piperazin-1-ylmethyl)-1H-benzo[d]imidazole;2-[(piperazin-1-yl)methyl]-1H-1,3-benzodiazole;SCHEMBL8690436;DTXSID50371898;BBL029151;STL352925;AKOS009158222;VS-09128;BB 0248219;CS-0270468;FT-0677627;EN300-145589

Suppliers and Price of 2-Piperazin-1-ylmethyl-1H-benzoimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Piperazin-1-ylmethyl-1H-benzoimidazole
1g
$ 378.00

Crysdot
2-(Piperazin-1-ylmethyl)-1H-benzo[d]imidazole 95+%
5g
$ 701.00

American Custom Chemicals Corporation
2-PIPERAZIN-1-YL METHYL-1H-BENZOIMIDAZOLE 95.00%
500MG
$ 777.32

Alichem
2-(Piperazin-1-ylmethyl)-1H-benzo[d]imidazole
5g
$ 729.24

AK Scientific
2-Piperazin-1-ylmethyl-1H-benzoimidazole
1g
$ 560.00

AccelPharmtech
2-(1-piperazinylmethyl)-1H-Benzimidazole 97.00%
25G
$ 3120.00

AccelPharmtech
2-(1-piperazinylmethyl)-1H-Benzimidazole 97.00%
5G
$ 1700.00

AccelPharmtech
2-(1-piperazinylmethyl)-1H-Benzimidazole 97.00%
1G
$ 1530.00

Total 9 raw suppliers

Chemical Property of 2-Piperazin-1-ylmethyl-1H-benzoimidazole

Chemical Property:

PSA：43.95000
LogP:1.23480
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:216.137496527
Heavy Atom Count:16
Complexity:227

Purity/Quality:

97% ^*data from raw suppliers

2-Piperazin-1-ylmethyl-1H-benzoimidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)CC2=NC3=CC=CC=C3N2

Technology Process of 2-Piperazin-1-ylmethyl-1H-benzoimidazole

There total 5 articles about 2-Piperazin-1-ylmethyl-1H-benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 110-85-0
piperazine

: 4857-04-9
2-chloromethyl-1H-benzimidazole

: 59052-85-6
2-(piperazin-1-ylmethyl)-1H-benzimidazole

Guidance literature:: In toluene; for 12h; Reflux;
DOI:10.1002/aoc.6005

Reference yield: 24.0%

: tert-butyl 4-((1H-benzo[d]imidazol-2-yl)methyl)piperazine-1-carboxylate

: 59052-85-6
2-(piperazin-1-ylmethyl)-1H-benzimidazole

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 4h;

Reference yield:

: 4857-04-9
2-chloromethyl-1H-benzimidazole

: 59052-85-6
2-(piperazin-1-ylmethyl)-1H-benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 20 °C

2: hydrogenchloride / methanol; 1,4-dioxane / 4 h / 20 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; methanol; acetonitrile;