N-Hydroxy-2-(2-pyridinylmethylene)hydrazinecarboximidamide mono(4-methylbenzenesulfonate) salt

Base Information

• Chemical Name: N-Hydroxy-2-(2-pyridinylmethylene)hydrazinecarboximidamide mono(4-methylbenzenesulfonate) salt
• CAS No.: 85894-16-2
• Molecular Formula: C₇H₈O₃S*C₇H₉N₅O
• Molecular Weight: 351.386
• Mol file: 85894-16-2.mol

Synonyms:

Chemical Property of N-Hydroxy-2-(2-pyridinylmethylene)hydrazinecarboximidamide mono(4-methylbenzenesulfonate) salt

Chemical Property:

• Vapor Pressure: 0.000223mmHg at 25°C
• Boiling Point: 325.9°C at 760 mmHg
• Flash Point: 150.9°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Hydroxy-2-(2-pyridinylmethylene)hydrazinecarboximidamide mono(4-methylbenzenesulfonate) salt

There total 3 articles about N-Hydroxy-2-(2-pyridinylmethylene)hydrazinecarboximidamide mono(4-methylbenzenesulfonate) salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.11%

pyridine-2-carbaldehyde (1121-60-4) + N-hydroxy-N'-aminoguanidine p-toluenesulphonate (36826-58-1) → 1-<(2-pyridylmethylene)amino>-3-hydroxyguanidine tosylate (85894-16-2)

Guidance literature:

DOI:10.1021/jm00368a024

Reference yield:

S-methylisothiosemicarbazide tosylate (36778-68-4) → 1-<(2-pyridylmethylene)amino>-3-hydroxyguanidine tosylate (85894-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 44.2 percent / hydroxylamine / 48 h / Ambient temperature

2: 46.11 percent

With hydroxylamine;

DOI:10.1021/jm00368a024

Reference yield:

methyl p-toluene sulfonate (80-48-8) → 1-<(2-pyridylmethylene)amino>-3-hydroxyguanidine tosylate (85894-16-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 135 g / CH₃OH / 18 h / Heating

2: 44.2 percent / hydroxylamine / 48 h / Ambient temperature

3: 46.11 percent

With methanol; hydroxylamine;

DOI:10.1021/jm00368a024

upstream raw materials:

pyridine-2-carbaldehyde

N-hydroxy-N'-aminoguanidine p-toluenesulphonate

S-methylisothiosemicarbazide tosylate

methyl p-toluene sulfonate