2,2-Difluoro-2-phenylacetamide

Base Information

Chemical Name:2,2-Difluoro-2-phenylacetamide
CAS No.:383-19-7
Molecular Formula:C8H7 F2 N O
Molecular Weight:171.146
Hs Code.:2924299090
European Community (EC) Number:630-936-0
NSC Number:111106
DSSTox Substance ID:DTXSID60296705
Wikidata:Q82037416
Mol file:383-19-7.mol

Synonyms:2,2-difluoro-2-phenylacetamide;383-19-7;Benzeneacetamide, a,a-difluoro-;MFCD00183287;2,2-Difluoro-2-phenyl-acetamide;NSC111106;Enamine_005921;a,a-Difluorophenylacetamide;a,a-Difluorobenzeneacetamide;SCHEMBL2465581;DTXSID60296705;HMS1410N03;alpha,alpha-difluorobenzeneacetamide;AC8926;STL205399;AKOS000116708;FS-4687;NSC-111106;IDI1_008156;2,2-bis(fluoranyl)-2-phenyl-ethanamide;SY131631;CS-0307634;FT-0632069;EN300-03862;A824107;Z56757372

Suppliers and Price of 2,2-Difluoro-2-phenylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2-Difluoro-2-phenylacetamide
1g
$ 155.00

SynQuest Laboratories
2,2-Difluoro-2-phenylacetamide 90%
25 g
$ 395.00

SynQuest Laboratories
2,2-Difluoro-2-phenylacetamide 90%
5 g
$ 150.00

SynQuest Laboratories
2,2-Difluoro-2-phenylacetamide 90%
1 g
$ 55.00

Oakwood
2,2-Difluoro-2-phenylacetamide 98%
1g
$ 40.00

Oakwood
2,2-Difluoro-2-phenylacetamide 98%
25g
$ 465.00

Oakwood
2,2-Difluoro-2-phenylacetamide 98%
5g
$ 155.00

Crysdot
2,2-Difluoro-2-phenylacetamide 97%
25g
$ 565.00

Apolloscientific
2,2-Difluoro-2-phenylacetamide 97%
5g
$ 228.00

Apolloscientific
2,2-Difluoro-2-phenylacetamide 97%
1g
$ 72.00

Total 18 raw suppliers

Chemical Property of 2,2-Difluoro-2-phenylacetamide

Chemical Property:

Vapor Pressure:0.000395mmHg at 25°C
Melting Point:114-115
Boiling Point:317°Cat760mmHg
Flash Point:145.5°C
PSA：43.09000
Density:1.269g/cm³
LogP:1.96400
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:171.04957017
Heavy Atom Count:12
Complexity:176

Purity/Quality:

97% ^*data from raw suppliers

2,2-Difluoro-2-phenylacetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(=O)N)(F)F

Technology Process of 2,2-Difluoro-2-phenylacetamide

There total 7 articles about 2,2-Difluoro-2-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1603-79-8
phenylglyoxylic acid ethyl ester

: 383-19-7
2,2-difluoro-2-phenylacetamide

Guidance literature:: With (diethylamino)sulfur trifluoride; In ethanol; hexane; ethyl acetate;

Reference yield: 47.0%

: 2169-67-7
2-bromo-2,2-difluoroacetamide

: 28557-00-8
phenylzinc chloride

: 383-19-7
2,2-difluoro-2-phenylacetamide

Guidance literature:: With (1,2-dimethoxyethane)dichloronickel(II); N,N,N,N,-tetramethylethylenediamine; (4R,4'R)-2,2'-(propane-2,2'diyl)bis(4-phenyl-4,5-dihydrooxazole); In tetrahydrofuran; at 0 ℃; Schlenk technique; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.orglett.6b00232