2,4-Bis(3,4-dimethoxyphenyl)butanoic acid

Base Information

• Chemical Name: 2,4-Bis(3,4-dimethoxyphenyl)butanoic acid
• CAS No.: 19611-19-9
• Molecular Formula: C₂₀H₂₄O₆
• Molecular Weight: 360.407
• NSC Number: 162498
• DSSTox Substance ID: DTXSID70303833
• Mol file: 19611-19-9.mol

Synonyms:19611-19-9;2,4-bis(3,4-dimethoxyphenyl)butanoic acid;NSC162498;homoveratrylhomoveratric acid;DTXSID70303833;NSC-162498

Chemical Property of 2,4-Bis(3,4-dimethoxyphenyl)butanoic acid

Chemical Property:

• Vapor Pressure: 1.82E-10mmHg at 25°C
• Boiling Point: 491.2°Cat760mmHg
• Flash Point: 168.4°C
• Density: 1.172g/cm³
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 360.15728848
• Heavy Atom Count: 26
• Complexity: 429

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)CCC(C2=CC(=C(C=C2)OC)OC)C(=O)O)OC

Technology Process of 2,4-Bis(3,4-dimethoxyphenyl)butanoic acid

There total 7 articles about 2,4-Bis(3,4-dimethoxyphenyl)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-bis-(3,4-dimethoxy-phenyl)-4-oxo-butyric acid (94757-88-7) → 2,4-bis-(3,4-dimethoxy-phenyl)-butyric acid (19611-19-9)

Guidance literature:

With hydrogenchloride; amalgamated zinc; toluene; weiteres Reagenz: Essigsaeure;

Reference yield:

2,4-bis-(3,4-dimethoxy-phenyl)-4-oxo-butyric acid amide (94577-55-6) → 2,4-bis-(3,4-dimethoxy-phenyl)-butyric acid (19611-19-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic NaOH-solution

2: amalgamated zinc; aqueous hydrochloric acid; toluene / weiteres Reagenz: Essigsaeure

With hydrogenchloride; sodium hydroxide; amalgamated zinc; toluene;

Reference yield:

2,4-bis(3,4-dimethoxyphenyl)-4-butyronitrilone (94685-52-6) → 2,4-bis-(3,4-dimethoxy-phenyl)-butyric acid (19611-19-9)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid; sulfuric acid

2: aq.-ethanolic NaOH-solution

3: amalgamated zinc; aqueous hydrochloric acid; toluene / weiteres Reagenz: Essigsaeure

With hydrogenchloride; sodium hydroxide; amalgamated zinc; sulfuric acid; acetic acid; toluene;

upstream raw materials:

2,4-bis-(3,4-dimethoxy-phenyl)-4-oxo-butyric acid

2,4-bis(3,4-dimethoxyphenyl)-4-butyronitrilone

2,4-bis-(3,4-dimethoxy-phenyl)-4-oxo-butyric acid amide

(E)-1-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one

Downstream raw materials:

N-[2-(3,4-dimethoxy-phenyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-[1]naphthyl]-formamide

2,3,8,9-tetramethoxy-4b,10b,11,12-tetrahydro-benzo[c]phenanthridine

6,7-dimethoxy-2-(3,4-dimethoxyphenyl)-1-tetralone

Refernces