(5Z)-3-(2,3-dimethylphenyl)-5-[(2-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

Base Information

Chemical Name:(5Z)-3-(2,3-dimethylphenyl)-5-[(2-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
CAS No.:5630-76-2
Molecular Formula:C7H7 N O3 S2
Molecular Weight:370.4454
Hs Code.:
DSSTox Substance ID:DTXSID90364441

Synonyms:(5Z)-3-(2,3-dimethylphenyl)-5-[(2-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one;301305-37-3;F0393-0228;(Z)-3-(2,3-dimethylphenyl)-5-(2-nitrobenzylidene)-2-thioxothiazolidin-4-one;5630-76-2;DTXSID90364441;STL035157;AKOS002201718;BIM-0026728.P001;(5Z)-3-(2,3-dimethylphenyl)-5-(2-nitrobenzylidene)-2-thioxo-1,3-thiazolidin-4-one

Suppliers and Price of (5Z)-3-(2,3-dimethylphenyl)-5-[(2-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of (5Z)-3-(2,3-dimethylphenyl)-5-[(2-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

Chemical Property:

Vapor Pressure:2.93E-12mmHg at 25°C
Boiling Point:552.7°C at 760 mmHg
Flash Point:288.1°C
Density:1.44g/cm³
XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:370.04458466
Heavy Atom Count:25
Complexity:602

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)N2C(=O)C(=CC3=CC=CC=C3[N+](=O)[O-])SC2=S)C
Isomeric SMILES:CC1=C(C(=CC=C1)N2C(=O)/C(=C/C3=CC=CC=C3[N+](=O)[O-])/SC2=S)C

Technology Process of (5Z)-3-(2,3-dimethylphenyl)-5-[(2-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

There total 2 articles about (5Z)-3-(2,3-dimethylphenyl)-5-[(2-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 701-23-5
(4-oxo-2-thioxo-thiazolidin-5-yl)-acetic acid

: 5630-76-2
(4-oxo-2-thioxo-thiazolidin-5-ylidene)-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Br₂ / acetic acid

2: HCl

With hydrogenchloride; bromine; In acetic acid;

Reference yield:

: 5316-60-9
(4-oxo-2-thioxo-thiazolidin-5-ylidene)-acetic acid

: 64-17-5
ethanol

: 5630-76-2
(4-oxo-2-thioxo-thiazolidin-5-ylidene)-acetic acid ethyl ester

Guidance literature:: With hydrogenchloride;

Reference yield: 90.0%

: 5630-76-2
(4-oxo-2-thioxo-thiazolidin-5-ylidene)-acetic acid ethyl ester

: 122-57-6
1-Phenylbut-1-en-3-one

: ethyl 4,8-dioxo-10-phenyl-2-thioxo-1-thia-3-azaspiro[4.5]decane-6-carboxylate

: 1397692-21-5
(5S,6S,10S)-ethyl 4,8-dioxo-10-phenyl-2-thioxo-1-thia-3-azaspiro[4.5]decane-6-carboxylate

Guidance literature:: With (S)-N¹-cyclohexyl-3,3-dimethylbutane-1,2-diamine; Boc-Trp-OH; In chloroform; at 50 ℃; for 72h; optical yield given as %ee; stereoselective reaction;
DOI:10.1039/c2cc34321e