Technology Process of 1,3,5-Benzenetriacetic acid
There total 5 articles about 1,3,5-Benzenetriacetic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1,3,5-Triethynylbenzene;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 1h;
With
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;
In
tetrahydrofuran;
for 2h;
With
oxone;
In
acetone;
at 50 ℃;
for 12h;
- Guidance literature:
-
With
oxone||potassium monopersulfate triple salt; water;
In
acetone;
at 50 ℃;
for 12h;
Inert atmosphere;
DOI:10.1002/anie.202000988
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / tetrahydrofuran; water / 3 h / 20 °C
2: potassium hydroxide / ethanol; water / 100 °C / Sealed tube
With
sodium hydrogencarbonate; potassium hydroxide;
In
tetrahydrofuran; ethanol; water;
DOI:10.1021/acs.jmedchem.1c01482
