eudistomin O

Base Information

• Chemical Name: eudistomin O
• CAS No.: 88704-40-9
• Molecular Formula: C₁₁H₇BrN₂
• Molecular Weight: 247.094
• Hs Code.: 2933990090
• Mol file: 88704-40-9.mol

Synonyms:7-Bromonorharman;Eudistomin O; Eudistomine O

Chemical Property of eudistomin O

Chemical Property:

• Vapor Pressure: 1.2E-07mmHg at 25°C
• Boiling Point: 443.6°C at 760 mmHg
• Flash Point: 222.1°C
• PSA: 28.68000
• Density: 1.699g/cm³
• LogP: 3.47860

Purity/Quality:

99% ^*data from raw suppliers

7-Bromo-9H-pyrido[3,4-b]indole 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of eudistomin O

There total 8 articles about eudistomin O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

7-bromo-1,2,3,4-tetrahydro-β-carboline (108061-47-8) → 7-bromo-9H-pyrido[3,4-b]indole (88704-40-9)

Guidance literature:

With diphenylselenium bis(trifluoroacetate); In 1,2-dimethoxyethane; for 19h;

DOI:10.1021/ja00245a031

Reference yield:

betacarboline (244-63-3) → 7-bromo-9H-pyrido[3,4-b]indole (88704-40-9)

Guidance literature:

With bromine; In tetrahydrofuran; sodium carbonate;

Reference yield:

7-bromo-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid (127286-63-9) → 7-bromo-9H-pyrido[3,4-b]indole (88704-40-9)

Guidance literature:

Multi-step reaction with 2 steps

1: conc HCl / H₂O / 0.75 h / Heating

2: 40 percent / Ph₂Se(OCOCF₃)2 / 1,2-dimethoxy-ethane / 19 h

With hydrogenchloride; diphenylselenium bis(trifluoroacetate); In 1,2-dimethoxyethane; water;

DOI:10.1021/ja00245a031

upstream raw materials:

7-bromo-1,2,3,4-tetrahydro-β-carboline

6-bromo-1H-indole

4-bromo-2-nitrotoluene

6-bromotryptamine

Downstream raw materials:

14-<(benzyloxy)methyl>didemnoline A