N-(2,5-Dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylbenzamide

Base Information

Chemical Name:N-(2,5-Dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylbenzamide
CAS No.:123039-60-1
Molecular Formula:C₂₈H₃₂N₂O
Molecular Weight:412.575
Hs Code.:
DSSTox Substance ID:DTXSID20924355
Mol file:123039-60-1.mol

Synonyms:BRN 3632068;N-(2,5-Dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylbenzamide;Benzamide, N-(2,5-dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenyl-;123039-60-1;DTXSID20924355;LS-26723;N-[2,5-Dimethyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylbenzamide

Suppliers and Price of N-(2,5-Dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2,5-Dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylbenzamide

Chemical Property:

Vapor Pressure:6.21E-12mmHg at 25°C
Boiling Point:544.9°Cat760mmHg
Flash Point:214.5°C
Density:1.089g/cm³
XLogP3:6.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:412.251463648
Heavy Atom Count:31
Complexity:545

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(C(CN1CCC2=CC=CC=C2)C)N(C3=CC=CC=C3)C(=O)C4=CC=CC=C4

Technology Process of N-(2,5-Dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylbenzamide

There total 4 articles about N-(2,5-Dimethyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 105115-49-9
(2,5-Dimethyl-1-phenethyl-piperidin-4-yl)-phenyl-amine

: 98-88-4
benzoyl chloride

: 123039-60-1
N-(2,5-Dimethyl-1-phenethyl-piperidin-4-yl)-N-phenyl-benzamide

Guidance literature:: With triethylamine; In benzene; for 7h; Ambient temperature;
DOI:10.1007/BF00758289

Reference yield:

: 29280-78-2
1-(2-phenylethyl)-2,5-dimethyl-4-piperidone

: 123039-60-1
N-(2,5-Dimethyl-1-phenethyl-piperidin-4-yl)-N-phenyl-benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / glacial acetic acid / toluene / Heating

2: 80 percent / sodium borohydride / methanol / 0.5 h / 20 °C

3: 50 percent / triethylamine / benzene / 7 h / Ambient temperature

With sodium tetrahydroborate; acetic acid; triethylamine; In methanol; toluene; benzene;
DOI:10.1007/BF00758289

Reference yield:

: 123039-70-3
[2,5-Dimethyl-1-phenethyl-piperidin-(4E)-ylidene]-phenyl-amine

: 123039-60-1
N-(2,5-Dimethyl-1-phenethyl-piperidin-4-yl)-N-phenyl-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / sodium borohydride / methanol / 0.5 h / 20 °C

2: 50 percent / triethylamine / benzene / 7 h / Ambient temperature

With sodium tetrahydroborate; triethylamine; In methanol; benzene;
DOI:10.1007/BF00758289