3-(1,2-Benzisoxazol-3-ylmethyl)-N-phenyl-1,2,4-thiadiazol-5-amine

Base Information

Chemical Name:3-(1,2-Benzisoxazol-3-ylmethyl)-N-phenyl-1,2,4-thiadiazol-5-amine
CAS No.:59899-85-3
Molecular Formula:C₁₆H₁₂N₄OS
Molecular Weight:308.363
Hs Code.:
DSSTox Substance ID:DTXSID201167192

Synonyms:DTXSID201167192;3-(1,2-Benzisoxazol-3-ylmethyl)-N-phenyl-1,2,4-thiadiazol-5-amine;59899-85-3

Suppliers and Price of 3-(1,2-Benzisoxazol-3-ylmethyl)-N-phenyl-1,2,4-thiadiazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(1,2-Benzisoxazol-3-ylmethyl)-N-phenyl-1,2,4-thiadiazol-5-amine

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:308.07318219
Heavy Atom Count:22
Complexity:366

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC2=NC(=NS2)CC3=NOC4=CC=CC=C43

Technology Process of 3-(1,2-Benzisoxazol-3-ylmethyl)-N-phenyl-1,2,4-thiadiazol-5-amine

There total 4 articles about 3-(1,2-Benzisoxazol-3-ylmethyl)-N-phenyl-1,2,4-thiadiazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50471-17-5
2-(benzo[d]isoxazol-3-yl)acetonitrile

: 59899-85-3
(3-benzo[d]isoxazol-3-ylmethyl-[1,2,4]thiadiazol-5-yl)-phenyl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: NH₂OH, HCl, aq. Na₂CO₃ / ethanol

2: CHCl₃ / 20 h / 70 °C

With hydrogenchloride; hydroxylamine; sodium carbonate; In ethanol; chloroform;
DOI:10.1248/cpb.24.632

Reference yield:

: 4865-84-3
2-(benzo[d]isoxazol-3-yl)acetic acid

: 59899-85-3
(3-benzo[d]isoxazol-3-ylmethyl-[1,2,4]thiadiazol-5-yl)-phenyl-amine

Guidance literature:: Multi-step reaction with 4 steps

1: (i) HCl, MeOH, (ii) NH₃

2: POCl₃ / 1.5 h / Heating

3: NH₂OH, HCl, aq. Na₂CO₃ / ethanol

4: CHCl₃ / 20 h / 70 °C

With hydrogenchloride; hydroxylamine; sodium carbonate; trichlorophosphate; In ethanol; chloroform;
DOI:10.1248/cpb.24.632

Reference yield:

: 23008-68-6
2-(benzo[d]isoxazol-3-yl)acetamide

: 59899-85-3
(3-benzo[d]isoxazol-3-ylmethyl-[1,2,4]thiadiazol-5-yl)-phenyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃ / 1.5 h / Heating

2: NH₂OH, HCl, aq. Na₂CO₃ / ethanol

3: CHCl₃ / 20 h / 70 °C

With hydrogenchloride; hydroxylamine; sodium carbonate; trichlorophosphate; In ethanol; chloroform;
DOI:10.1248/cpb.24.632