(E)-1,1,1-Trichloro-4-ethoxy-but-3-en-2-one

Base Information

• Chemical Name: (E)-1,1,1-Trichloro-4-ethoxy-but-3-en-2-one
• CAS No.: 59938-07-7
• Molecular Formula: C6H7Cl3O2
• Molecular Weight: 217.479
• Mol file: 59938-07-7.mol

Synonyms:(3E)-1,1,1-TRICHLORO-4-ETHOXYBUT-3-EN-2-ONE;1,1,1-Trichloro-4-ethoxy-but-3-en-2-one;

Chemical Property of (E)-1,1,1-Trichloro-4-ethoxy-but-3-en-2-one

Chemical Property:

• Boiling Point: 84-86 °C(Press: 1 Torr)
• PSA: 26.30000
• Density: 1.368±0.06 g/cm3(Predicted)
• LogP: 2.47590

Purity/Quality:

97% ^*data from raw suppliers

1,1,1-Trichloro-4-ethoxy-but-3-en-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-1,1,1-Trichloro-4-ethoxy-but-3-en-2-one

There total 3 articles about (E)-1,1,1-Trichloro-4-ethoxy-but-3-en-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethyl vinyl ether (109-92-2,25104-37-4) + trifluoroacetyl chloride (76-02-8) → (3E)-1,1,1-trichloro-4-ethoxybut-3-en-2-one (59938-07-7)

Guidance literature:

at 0 - 25 ℃;

DOI:10.1021/acs.oprd.0c00301

Reference yield:

ethyl vinyl ether (109-92-2,25104-37-4) + trichloroacetic acid anhydride (4124-31-6) → (3E)-1,1,1-trichloro-4-ethoxybut-3-en-2-one (59938-07-7)

Guidance literature:

With pyridine; In dichloromethane;

DOI:10.1246/cl.1976.499

Reference yield:

1,1,1,4-tetrachloro-4-ethoxy-butan-2-one (83124-64-5) → (3E)-1,1,1-trichloro-4-ethoxybut-3-en-2-one (59938-07-7)

Guidance literature:

Heating;

DOI:10.1080/15257770500446931

upstream raw materials:

ethyl vinyl ether

trichloroacetic acid anhydride

trifluoroacetyl chloride

1,1,1,4-tetrachloro-4-ethoxy-butan-2-one

Downstream raw materials:

ethyl 3,3-diethoxypropanoate

1,1,1-Trichloro-4-(-)-menthyloxy-3-buten-2-one

(E)-3-ethoxyprop-2-enoic acid

5-hydroxy-5-trichloromethyl-4,5-dihydroisoxazole