4(1H)-Pyrimidinone, 2,3-dihydro-5-(phenylmethyl)-2-thioxo-

Base Information

Chemical Name:4(1H)-Pyrimidinone, 2,3-dihydro-5-(phenylmethyl)-2-thioxo-
CAS No.:25912-36-1
Molecular Formula:C11H10 N2 O S
Molecular Weight:218.279
Hs Code.:2933599090
NSC Number:78394
DSSTox Substance ID:DTXSID50398404
Nikkaji Number:J696.876G
Mol file:25912-36-1.mol

Synonyms:25912-36-1;4(1H)-Pyrimidinone, 2,3-dihydro-5-(phenylmethyl)-2-thioxo-;5-benzyl-2-sulfanylidene-1H-pyrimidin-4-one;4(1H)-Pyrimidinone,2,3-dihydro-5-(phenylmethyl)-2-thioxo-;NSC78394;5-[Benzyl]-2-thiouracil;SCHEMBL4418633;DTXSID50398404;NSC-78394;FT-0758756;5-benzyl-2-sulfanyl-3,4-dihydropyrimidin-4-one;EN300-6738669;Z3251702531;5-Benzyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one

Suppliers and Price of 4(1H)-Pyrimidinone, 2,3-dihydro-5-(phenylmethyl)-2-thioxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4(1H)-Pyrimidinone,2,3-dihydro-5-(phenylmethyl)-2-thioxo-
2.5g
$ 1155.00

AK Scientific
4(1H)-Pyrimidinone,2,3-dihydro-5-(phenylmethyl)-2-thioxo-
1g
$ 637.00

Total 3 raw suppliers

Chemical Property of 4(1H)-Pyrimidinone, 2,3-dihydro-5-(phenylmethyl)-2-thioxo-

Chemical Property:

PSA：80.74000
Density:1.32g/cm³
LogP:2.02330
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:218.05138412
Heavy Atom Count:15
Complexity:306

Purity/Quality:

99% ^*data from raw suppliers

4(1H)-Pyrimidinone,2,3-dihydro-5-(phenylmethyl)-2-thioxo- ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC2=CNC(=S)NC2=O

Technology Process of 4(1H)-Pyrimidinone, 2,3-dihydro-5-(phenylmethyl)-2-thioxo-

There total 8 articles about 4(1H)-Pyrimidinone, 2,3-dihydro-5-(phenylmethyl)-2-thioxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98516-80-4,2016-00-4
ethyl 2-formyl-3-phenylpropionate

: 17356-08-0
thiourea

: 25912-36-1
5-benzyl-2-tioxo-2,3-dihydro-pyrimidine-4(1H)-one

Guidance literature:: With sodium ethanolate;
DOI:10.1021/ja01279a032

Reference yield:

: C₁₂H₁₄N₂O₂S

: 25912-36-1
5-benzyl-2-tioxo-2,3-dihydro-pyrimidine-4(1H)-one

Guidance literature:: With potassium carbonate; In acetonitrile; at 50 ℃; for 6h;
DOI:10.1055/s-0036-1588947

Reference yield:

: 2021-28-5
ethyl dihydrocinnamate

: 25912-36-1
5-benzyl-2-tioxo-2,3-dihydro-pyrimidine-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / mineral oil; 1,2-dimethoxyethane / 18 h / 20 °C

2: sodium methylate / methanol / 17 h / Reflux

With sodium methylate; sodium hydride; In methanol; 1,2-dimethoxyethane; mineral oil;