Technology Process of Propanedioic acid, (phenylmethyl)-, mono(1,1-dimethylethyl) ester
There total 5 articles about Propanedioic acid, (phenylmethyl)-, mono(1,1-dimethylethyl) ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
bromobenzene; tert-Butyl acrylate; carbon dioxide;
With
4,4'-Dimethoxy-2,2'-bipyridin; trimethylaluminum; lithium chloride; cobalt(II) chloride; zinc;
In
N,N-dimethyl-formamide; toluene; acetonitrile;
at 40 ℃;
for 14h;
under 760.051 Torr;
Schlenk technique;
With
hydrogenchloride;
In
water;
at 0 ℃;
DOI:10.1002/cssc.202101963
- Guidance literature:
-
iodobenzene; tert-Butyl acrylate; carbon dioxide;
With
4,4'-Dimethoxy-2,2'-bipyridin; trimethylaluminum; lithium chloride; cobalt(II) chloride; zinc;
In
N,N-dimethyl-formamide; toluene; acetonitrile;
at 40 ℃;
for 14h;
under 760.051 Torr;
Schlenk technique;
With
hydrogenchloride;
In
water;
at 0 ℃;
DOI:10.1002/cssc.202101963
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere
1.2: 8 h / 2 °C / Inert atmosphere
2.1: potassium hydroxide; methanol / 3 h / 0 °C
With
methanol; sodium hydride; potassium hydroxide;
In
N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/anie.201802805
