Technology Process of Boronic acid, [4-[3,6-bis(1,1-dimethylethyl)-9H-carbazol-9-yl]phenyl]-
There total 10 articles about Boronic acid, [4-[3,6-bis(1,1-dimethylethyl)-9H-carbazol-9-yl]phenyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3,6-di-tert-butyl-9-(4-iodophenyl)-9H-carbazole;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
With
triethyl borate;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 26h;
With
hydrogenchloride;
In
diethyl ether;
for 1h;
DOI:10.1021/ja060936t
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 99 percent / AlCl3 / 22 h
2.1: 91.2 percent / SnCl2*2H2O / ethanol / 6 h / Heating
3.1: hydrochloric acid; NaNO2 / dioxane; H2O
3.2: 65.9 percent / KI / dioxane; H2O / 0.5 h / 70 - 80 °C
4.1: n-BuLi / tetrahydrofuran / 0.5 h / -78 °C
4.2: B(OEt3)3 / tetrahydrofuran / 26 h / -78 - 20 °C
4.3: 59 percent / hydrochloric acid / diethyl ether / 1 h
With
hydrogenchloride; n-butyllithium; aluminium trichloride; tin(ll) chloride; sodium nitrite;
In
tetrahydrofuran; 1,4-dioxane; ethanol; water;
DOI:10.1021/ja060936t
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: KOH / 350 °C
1.2: 72 percent / 48 h / 55 °C
2.1: 99 percent / AlCl3 / 22 h
3.1: 91.2 percent / SnCl2*2H2O / ethanol / 6 h / Heating
4.1: hydrochloric acid; NaNO2 / dioxane; H2O
4.2: 65.9 percent / KI / dioxane; H2O / 0.5 h / 70 - 80 °C
5.1: n-BuLi / tetrahydrofuran / 0.5 h / -78 °C
5.2: B(OEt3)3 / tetrahydrofuran / 26 h / -78 - 20 °C
5.3: 59 percent / hydrochloric acid / diethyl ether / 1 h
With
hydrogenchloride; potassium hydroxide; n-butyllithium; aluminium trichloride; tin(ll) chloride; sodium nitrite;
In
tetrahydrofuran; 1,4-dioxane; ethanol; water;
DOI:10.1021/ja060936t
