2-Furancarbonyl chloride, 5-(4-bromophenyl)-

Base Information

• Chemical Name: 2-Furancarbonyl chloride, 5-(4-bromophenyl)-
• CAS No.: 60335-98-0
• Molecular Formula: C11H6BrClO2
• Molecular Weight: 285.524
• Mol file: 60335-98-0.mol

Synonyms:

Chemical Property of 2-Furancarbonyl chloride, 5-(4-bromophenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Furancarbonyl chloride, 5-(4-bromophenyl)-

There total 4 articles about 2-Furancarbonyl chloride, 5-(4-bromophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

5-(4-bromophenyl)furan-2-carboxylic acid (52938-96-2) → 5-(4-bromo-phenyl)-furan-2-carbonyl chloride (60335-98-0)

Guidance literature:

With thionyl chloride; In benzene; Reflux;

DOI:10.1134/S1070428009040125

Reference yield:

4-bromo-aniline (106-40-1) → 5-(4-bromo-phenyl)-furan-2-carbonyl chloride (60335-98-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite; hydrogenchloride

2: thionyl chloride / benzene / 3 h / Reflux

With hydrogenchloride; thionyl chloride; sodium nitrite; In benzene; 1: |Meerwein Arylation;

DOI:10.2174/1570180811666140220005252

Reference yield:

2-furanoic acid (88-14-2) → 5-(4-bromo-phenyl)-furan-2-carbonyl chloride (60335-98-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite; hydrogenchloride

2: thionyl chloride / benzene / 3 h / Reflux

With hydrogenchloride; thionyl chloride; sodium nitrite; In benzene; 1: |Meerwein Arylation;

DOI:10.2174/1570180811666140220005252

upstream raw materials:

5-(4-bromophenyl)furan-2-carboxylic acid

4-bromo-aniline

2-furanoic acid

Downstream raw materials:

{[1-[5-(4-Bromo-phenyl)-furan-2-yl]-1-chloro-meth-(Z)-ylidene]-amino}-acetic acid ethyl ester

{5-[5-(4-Bromo-phenyl)-furan-2-yl]-tetrazol-1-yl}-acetic acid

{5-[5-(4-Bromo-phenyl)-furan-2-yl]-tetrazol-1-yl}-acetic acid ethyl ester

[5-(4-bromophenyl)furan-2-yl]methanol