3,5-Pyridinedicarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4-[6-(ethoxycarb onyl)-3-pyridazinyl]-6-[(4-fluorophenyl)methyl]-, diethyl ester

Base Information

Chemical Name:3,5-Pyridinedicarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4-[6-(ethoxycarb onyl)-3-pyridazinyl]-6-[(4-fluorophenyl)methyl]-, diethyl ester
CAS No.:604000-43-3
Molecular Formula:C34H39FN4O8
Molecular Weight:650.704
Hs Code.:

3,5-Pyridinedicarboxylic acid,
2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4-[6-(ethoxycarb
onyl)-3-pyridazinyl]-6-[(4-fluorophenyl)methyl]-, diethyl ester

Synonyms:

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Chemical Property of 3,5-Pyridinedicarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4-[6-(ethoxycarb onyl)-3-pyridazinyl]-6-[(4-fluorophenyl)methyl]-, diethyl ester

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Technology Process of 3,5-Pyridinedicarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4-[6-(ethoxycarb onyl)-3-pyridazinyl]-6-[(4-fluorophenyl)methyl]-, diethyl ester

There total 1 articles about 3,5-Pyridinedicarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]-4-[6-(ethoxycarb onyl)-3-pyridazinyl]-6-[(4-fluorophenyl)methyl]-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 604000-39-7
diethyl 2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidinyl]-4-[6-(ethoxycarbonyl)-3-pyridazinyl]-6-(4-fluorobenzyl)-1,4-dihydro-3,5-pyridinedicarboxylate

: 604000-43-3
diethyl 2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidinyl]-4-[6-(ethoxycarbonyl)-3-pyridazinyl]-6-(4-fluorobenzyl)-3,5-pyridinedicarboxylate

Guidance literature:: With ammonium cerium(IV) nitrate; In water; acetonitrile; for 0.0833333h;

Reference yield:

: 604000-43-3
diethyl 2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidinyl]-4-[6-(ethoxycarbonyl)-3-pyridazinyl]-6-(4-fluorobenzyl)-3,5-pyridinedicarboxylate

: ethyl 4-[6-(ethoxycarbonyl)-3-pyridazinyl]-2-(4-fluorobenzyl)-5-oxo-7,8,9,9a-tetrahydro-5H-pyrido[2,3-a]pyrrolizine-3-carboxylate

Guidance literature:: diethyl 2-[(2S)-1-(tert-butoxycarbonyl)pyrrolidinyl]-4-[6-(ethoxycarbonyl)-3-pyridazinyl]-6-(4-fluorobenzyl)-3,5-pyridinedicarboxylate; With trifluoroacetic acid; In dichloromethane; for 1h;

With triethylamine; In dichloromethane; for 2h;